Profile of Mothers of Children with Fetal Alcohol Spectrum Disorder: A Population-Based Study in Canada.
Profile of Mothers of Children with Fetal Alcohol Spectrum Disorder: A Population-Based Study in Canada.
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DOI：
10.3390/ijerph17217986
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发表时间：
2020-10-30
影响因子：
--
通讯作者：
Rehm J
中科院分区：
文献类型：
--
作者：
Popova S;Lange S;Temple V;Poznyak V;Chudley AE;Burd L;Murray M;Rehm J
目的：比较胎儿酒精谱系障碍（FASD）儿童的母亲与典型发育对照儿童的母亲的特征。方法：本研究采用横断面、观察性设计，采用主动病例确定。使用标准化的回顾性问卷对亲生母亲进行了访谈，以收集有关人口统计学、生活环境、妊娠史、营养、酒精和其他药物使用的数据。结果：共有173名母亲接受了采访。其中，19名儿童被诊断患有FASD，5名儿童接受了延迟的FASD诊断，37名儿童被选入对照组作为典型发育儿童。其余112名母亲的孩子不符合FASD的诊断标准。FASD儿童的母亲与对照组儿童的母亲在怀孕时的年龄、种族、婚姻状况和就业状况方面没有显著差异。然而，与对照组儿童的母亲相比，FASD儿童的母亲受教育程度较低（p < 0.01），在怀孕时更有可能接受经济支持（p < 0.05），吸烟（p < 0.001），在怀孕前使用大麻或印度大麻（p < 0.01）。所有患有FASD的儿童的母亲在怀孕确认之前都报告饮酒;然而，只有10.5%的人在怀孕确认之后报告饮酒。接受采访的母亲中没有人报告在怀孕确认后使用任何药物。结论：需要采取以人群为基础的预防性干预措施，包括在怀孕前和怀孕期间反复筛查、监测和教育酒精使用以及其他物质的影响，以消除FASD的风险和对儿童和孕产妇健康的其他负面影响。
Objective: To compare the characteristics of mothers of children with Fetal Alcohol Spectrum Disorder (FASD) with mothers of typically developing control children. Methods: The study utilized a cross-sectional, observational design, using active case ascertainment. Biological mothers were interviewed using a standardized retrospective questionnaire to collect data on demographics, living environment, pregnancy history, nutrition, alcohol and other drug use prior to and following pregnancy recognition. Results: A total of 173 mothers were interviewed. Of these, 19 had a child who was diagnosed with FASD, five had a child who had received a deferred FASD diagnosis, and 37 had children who were selected into the control group as typically developing children. The remaining 112 mothers had children who did not meet diagnostic criteria for FASD. The mothers of children with FASD did not differ significantly from mothers of the control group children with respect to age, ethnicity, marital status, and employment status at the time of pregnancy. However, mothers of children with FASD had lower levels of education (p < 0.01) and were more likely to have received financial support (p < 0.05) at the time of pregnancy, to have smoked tobacco (p < 0.001), and to have used marijuana or hashish (p < 0.01) prior to pregnancy recognition, compared with mothers of control children. All mothers of children with FASD reported alcohol consumption prior to pregnancy recognition; however, only 10.5% reported alcohol consumption following pregnancy recognition. None of the mothers interviewed reported any drug use following pregnancy recognition. Conclusions: Population-based preventive interventions, including repeated screening, monitoring, and education regarding the effects of alcohol use, as well as other substances, before and during pregnancy, are needed to eliminate risk for FASD and other negative consequences on child and maternal health.
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影响因子：
2.3
作者：
Li, Qing;Fisher, Wayne W.;Burd, Larry
通讯作者：
Burd, Larry
影响因子：
12.7
作者：
May, PA;Gossage, JP;Viljoen, DL
通讯作者：
Viljoen, DL
影响因子：
2.9
作者：
ABEL, EL
通讯作者：
ABEL, EL
影响因子：
4.2
作者：
Chang, Judy C.;Tarr, Jill A.;Arnold, Robert M.
通讯作者：
Arnold, Robert M.
DOI：
10.1136/eb-2013-101346
发表时间：
2014-02-01
期刊：
Evidence-based medicine
影响因子：
--
作者：
Burd, Larry
通讯作者：
Burd, Larry