The effects of genetic background on exercise performance in Drosophila.

The effects of genetic background on exercise performance in Drosophila.
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DOI:
10.1080/19336934.2020.1835329
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发表时间:
2020-03
期刊:
Fly
影响因子:
1.2
通讯作者:
Wessells R
Wessells R
中科院分区:
生物学4区
文献类型:
--
作者:
Damschroder D;Richardson K;Cobb T;Wessells R

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在过去的十年里,使用果蝇模型来研究运动训练的广泛益处的情况有所增加。随着使用果蝇作为运动模型的工作变得越来越普遍,应该检查遗传背景对表现的影响,以便更好地了解它对用于定量测量和比较运动表型的评估的影响。在本文中,我们综述了各种运动训练果蝇的方法,以及不同野生型果蝇品系对各种运动反应的生理评估。最后,我们总结了常用菌株的性能趋势。
The use of the Drosophila model for studying the broad beneficial effects of exercise training has grown over the past decade. As work using Drosophila as an exercise model becomes more widespread, the influence of genetic background on performance should be examined in order to better understand its influence on assessments used to quantitatively measure and compare exercise phenotypes. In this article, we review the various methods of exercise training Drosophila, and the performance of different wild-type Drosophila strains on various physiological assessments of exercise response. We conclude by summarizing the performance trends of commonly used strains.
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