Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion.
Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion.
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白内障手术与视网膜静脉阻塞风险降低无关。
DOI：
10.1016/j.xops.2021.100041
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发表时间：
2021-09
影响因子：
--
通讯作者：
IRIS Registry Analytic Ctr Study Grp
中科院分区：
文献类型：
--
作者：
Bagdasarova, Yelena;Lee, Aaron Y.;Maring, Morgan;Wen, Joanne;Lacy, Megan;Lee, Cecilia S.;Chen, Andrew;IRIS Registry Analytic Ctr Study Grp
使用美国眼科学会智能视觉研究（IRIS®）登记研究评估白内障手术是否与视网膜中央静脉阻塞（CRVO）或视网膜分支静脉阻塞（BRVO）发病风险降低相关。IRIS登记数据的回顾性数据库研究。使用决策树分类器作为倾向模型，将IRIS登记处接受白内障手术的患者与IRIS登记处的对照参与者进行1：1匹配。对照组和治疗组最初使用无并发症白内障手术的当前手术术语代码和其他直接标准选择。为了实现治疗-对照匹配，训练决策树分类器，以基于一组选定的治疗预测因子将患者分类为治疗与对照，其中最佳矫正视力和年龄是最重要的预测因子。随后，使用分类器、访问日期和实践标识对治疗和对照参与者进行匹配。对匹配组进行考克斯回归，以测量视网膜静脉阻塞发展的风险比（HR），调整了年龄、性别、种族、主要保险类型和既往糖尿病视网膜病变（DR）、青光眼和窄角的诊断。接受白内障手术的患者与匹配的对照参与者相比发生视网膜静脉阻塞的HR。在白内障手术后或基线访视后的第一年，接受白内障手术的患者与未接受手术的对照组患者相比，CRVO和BRVO的HR分别为1.26 [95%置信区间[CI]，1.16-1.38; P < 0.001]和1.27 [95% CI，1.19-1.36;在控制了年龄、性别、种族、保险、DR、青光眼和窄角病史后，P < 0.001]。糖尿病视网膜病变是白内障手术后发生CRVO（2.79 [95%CI，2.43-3.20; P < 0.001]）和BRVO（2.35 [95%CI，2.09-2.64; P < 0.001]）的最强预测因子。白内障手术与第一年内视网膜静脉阻塞风险的小幅增加相关;然而，发病率很低，可能没有临床意义。
To evaluate whether cataract surgery is associated with decreased risks of central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) development using the American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry. Retrospective database study of the IRIS Registry data. Patients in the IRIS Registry who underwent cataract surgery and 1:1 matched control participants from the IRIS Registry using a decision tree classifier as a propensity model. Control and treatment groups initially were selected using Current Procedural Terminology codes for uncomplicated cataract surgery and other straightforward criteria. To accomplish treatment–control matching, a decision tree classifier was trained to classify patients as treatment versus control based on a set of chosen predictors for treatment, where best-corrected visual acuity and age were the most important predictors. Treatment and control participants subsequently were matched using the classifier, the visit dates, and the identifications of the practice. Cox regression was performed on the matched groups to measure the hazard ratio (HR) of retinal vein occlusion development adjusted for age, sex, race, primary insurance type, and previous diagnosis of diabetic retinopathy (DR), glaucoma, and narrow angles. The HR of retinal vein occlusion developing in patients who underwent cataract surgery compared with matched control participants. The HRs for CRVO and BRVO developing in patients who underwent cataract surgery compared with matched control participants who did not during the first year after either cataract surgery or baseline visit were 1.26 [95% confidence interval [CI], 1.16–1.38; P < 0.001] and 1.27 [95% CI, 1.19–1.36; P < 0.001], respectively, after controlling for age, sex, race, insurance, and history of DR, glaucoma, and narrow angles. Diabetic retinopathy was the strongest predictor associated with CRVO (2.79 [95% CI, 2.43–3.20; P < 0.001]) and BRVO (2.35 [95% CI, 2.09–2.64; P < 0.001]) development after cataract surgery. Cataract surgery is associated with a small increase in risk of retinal vein occlusions within the first year; however, the incidence is low and likely not clinically significant.
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影响因子：
4.4
作者：
Cheung, Ning;Klein, Ronald;Wong, Tien Yin
通讯作者：
Wong, Tien Yin
影响因子：
13.7
作者：
Chiang, Michael F.;Sommer, Alfred;Parke, David W., II
通讯作者：
Parke, David W., II
DOI：
10.1097/j.jcrs.0000000000000337
发表时间：
2020-11-01
影响因子：
2.8
作者：
Aggarwal, Shruti;Jain, Punya;Jain, Amit
通讯作者：
Jain, Amit
影响因子：
4.4
作者：
Arakawa, Satoshi;Yasuda, Miho;Ishibashi, Tatsuro
通讯作者：
Ishibashi, Tatsuro
吸烟与较高的眼内压有关，无论青光眼如何：使用智能研究（IRIS®）注册中心对1,250万患者的回顾性研究。
影响因子：
--
作者：
Lee CS;Owen JP;Yanagihara RT;Lorch A;Pershing S;Hyman L;Miller JW;Haller JA;Chiang MF;Lum F;Lee AY
通讯作者：
Lee AY