Identification of infected cell-specific monoclonal antibodies and their role in host resistance to ocular herpes simplex virus type 1 infection.
Identification of infected cell-specific monoclonal antibodies and their role in host resistance to ocular herpes simplex virus type 1 infection.
复制标题
感染细胞特异性单克隆抗体的鉴定及其在宿主抵抗 1 型眼部单纯疱疹病毒感染中的作用。
DOI:
10.1099/0022-1317-65-3-657
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发表时间:
1984
期刊:
影响因子:
--
通讯作者:
Oakes,JE
中科院分区:
文献类型:
--
作者:
Rector,JT;Lausch,RN;Oakes,JE
Monoclonal antibodies 35S and 55S, specific for herpes simplex virus type 1 (HSV-1) glycoproteins gB and gD respectively, were found to react with infected cell membranes but not cell-free virions. This indicates that the spectrum of viral determinants detectable on the infected cell surface is not identical to that detectable on the virion envelope. The monoclonal antibody 35S could promote recovery from ocular HSV-1 infection in mice. Thus, antibody reactive with infective cell-specific determinants can play a significant role in host resistance to HSV-1 infection.
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DOI:
10.1084/jem.154.3.676
发表时间:
1981-09-01
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Nisbet-Brown E;Singh B;Diener E
通讯作者:
Diener E
DOI:
--
发表时间:
1981
影响因子:
11.1
作者:
L. Pereira;D. Dondero;B. Norrild;B. Roizman
通讯作者:
B. Roizman
影响因子:
4.4
作者:
D. Wylie;N. Klinman
通讯作者:
D. Wylie;N. Klinman
影响因子:
3.1
作者:
N. Balachandran;S. Bacchetti;W. Rawls
通讯作者:
W. Rawls
影响因子:
5.4
作者:
Robert B. Baucke;Patrícia;G. Spear
通讯作者:
G. Spear