Cytotoxicity of Ni from Surface-Treated Porous Nitinol (PNT) on Osteoblast Cells.
Cytotoxicity of Ni from Surface-Treated Porous Nitinol (PNT) on Osteoblast Cells.
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DOI：
10.1007/s11665-011-9930-3
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发表时间：
2011-07-01
影响因子：
2.3
通讯作者：
McGoron, A.
中科院分区：
文献类型：
--
作者：
Pulletikurthi, C.;Munroe, N.;Gill, P.;Pandya, S.;Persaud, D.;Haider, W.;Iyer, K.;McGoron, A.
多孔镍钛诺（PNT）表面的镍浸出主要取决于其表面特性，可通过适当的表面处理加以控制。在本研究中，PNT进行了两种表面处理，即水沸腾和干热钝化。采用磷酸缓冲盐水（PBS）溶液对PNT进行循环电位极化试验，用硫代丹B （SRB）法评价其中含镍对成骨细胞的细胞毒性。此外，外源性添加相似浓度的镍到细胞培养基中，以确定对成骨细胞的细胞毒性作用。采用扫描电镜和原子力显微镜观察未经处理和表面处理的纳米管的形貌。在PNT表面观察到人成骨细胞的生长。
The leaching of nickel from the surface of porous Nitinol (PNT) is mainly dependent on its surface characteristics, which can be controlled by appropriate surface treatments. In this investigation, PNT was subjected to two surface treatments, namely, water-boiling and dry-heating passivations. Phosphate buffer saline (PBS) solutions obtained from cyclic potentiodynamic polarization tests on PNT were employed to assess the cytotoxicity of Ni contained therein on osteoblast cells by Sulforhodamine B (SRB) assay. In addition, similar concentrations of Ni were added exogenously to cell culture media to determine cytotoxic effects on osteoblast cells. The morphologies of the untreated and the surface-treated PNTs were examined using SEM and AFM. Furthermore, growth of human osteoblast cells was observed on the PNT surfaces.
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影响因子：
14
作者：
Kapanen, A;Ilvesaro, J;Tuukkanen, J
通讯作者：
Tuukkanen, J
影响因子：
9.7
作者：
Chrzanowski, Wojciech;Abou Neel, Ensanya Ali;Knowles, Jonathan Campbell
通讯作者：
Knowles, Jonathan Campbell
DOI：
10.1007/s11665-009-9435-5
发表时间：
2009-08-01
影响因子：
2.3
作者：
Haider, Waseem;Munroe, Norman;Amruthaluri, Sushma
通讯作者：
Amruthaluri, Sushma
DOI：
10.1007/s11665-009-9454-2
发表时间：
2009-08-01
影响因子：
2.3
作者：
Munroe, Norman;Pulletikurthi, Chandan;Haider, Waseem
通讯作者：
Haider, Waseem
影响因子：
14
作者：
Setzer, Bernhard;Baechle, Maria;Kohal, Ralf J.
通讯作者：
Kohal, Ralf J.