The role of vasopressin in olfactory and visual processing.

The role of vasopressin in olfactory and visual processing.
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DOI:
10.1007/s00441-018-2867-1
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发表时间:
2019-01
影响因子:
3.6
通讯作者:
Ludwig M
Ludwig M
中科院分区:
生物学3区
文献类型:
--
作者:
Wacker D;Ludwig M

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神经加压素是脊椎动物行为的有力调节器。它在感觉加工区域和更大的调节网络内发挥作用,调节社会认知、联系、攻击性、交流和其他社会行为的变化。大脑中有多种加压素神经元,包括嗅觉和视觉处理区域。最近利用一种增强型绿色荧光蛋白-加压素(EGFP-VP)转基因大鼠发现了一些加压素神经元,如主、副嗅球、前嗅核、梨状皮质和视网膜中的加压素神经元。基于加压素产生区和敏感脑区的相互联系,并考虑到与躯体-树突释放相关的自分泌、旁分泌和神经激素样作用,我们讨论了这些不同的神经元群体如何相互作用来影响行为。
Neural vasopressin is a potent modulator of behaviour in vertebrates. It acts at both sensory processing regions and within larger regulatory networks to mediate changes in social recognition, affiliation, aggression, communication and other social behaviours. There are multiple populations of vasopressin neurons within the brain, including groups in olfactory and visual processing regions. Some of these vasopressin neurons, such as those in the main and accessory olfactory bulbs, anterior olfactory nucleus, piriform cortex and retina, were recently identified using an enhanced green fluorescent protein-vasopressin (eGFP-VP) transgenic rat. Based on the interconnectivity of vasopressin-producing and sensitive brain areas and in consideration of autocrine, paracrine and neurohormone-like actions associated with somato-dendritic release, we discuss how these different neuronal populations may interact to impact behaviour.
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