Species, sex and individual differences in the vasotocin/vasopressin system: relationship to neurochemical signaling in the social behavior neural network.

Species, sex and individual differences in the vasotocin/vasopressin system: relationship to neurochemical signaling in the social behavior neural network.
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DOI:
10.1016/j.yfrne.2014.07.001
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发表时间:
2015-01
影响因子:
7.4
通讯作者:
Albers, H. Elliott
Albers, H. Elliott
中科院分区:
医学1区
文献类型:
--
作者:
Albers, H. Elliott

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精氨酸-催产素(精氨酸-vasotocin,AVT)/精氨酸加压素(arginine vasopressin,AVP)是AVP/催产素(oxytocin,OT)超家族成员,参与社会行为、社会认知和情绪的调节。比较研究表明,AVT/AVP及其受体存在于整个“社会行为神经网络”中,并显示出控制社会行为的信号系统所预期的特性(即,物种、性别和个体差异以及性腺激素和社会因素的调节)。SBNN内的神经化学信号传导可能涉及共同释放多种化学信号(例如,经典神经递质和AVT/AVP以及其它肽)和非突触机制(即,体积传输)。SBNN内AVP/OT肽和受体之间的串扰是可能的。更好地了解SBNN中神经化学信号的功能特性将允许更精细地检查该肽系统与物种,性别和社会性个体差异之间的关系。
Arginine-vasotocin(AVT)/arginine vasopressin (AVP) are members of the AVP/oxytocin (OT) superfamily of peptides that are involved in the regulation of social behavior, social cognition and emotion. Comparative studies have revealed that AVT/AVP and their receptors are found throughout the “Social Behavior Neural Network” and display the properties expected from a signaling system that controls social behavior (i.e., species, sex and individual differences and modulation by gonadal hormones and social factors). Neurochemical signaling within the SBNN likely involves a complex combination of synaptic mechanisms that co-release multiple chemical signals (e.g., classical neurotransmitters and AVT/AVP as well as other peptides) and non-synaptic mechanisms (i.e., volume transmission). Crosstalk between AVP/OT peptides and receptors within the SBNN is likely. A better understanding of the functional properties of neurochemical signaling in the SBNN will allow for a more refined examination of the relationships between this peptide system and species, sex and individual differences in sociality.
DOI: 10.1111/j.1432-1033.1996.0759p.x
发表时间: 1996-05-01
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