Epidemiological and virological characteristics of respiratory tract infections in children during COVID-19 outbreak.
Epidemiological and virological characteristics of respiratory tract infections in children during COVID-19 outbreak.
复制标题
COVID-19爆发期间儿童呼吸道感染的流行病学和病毒学特征
DOI：
10.1186/s12887-021-02654-8
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发表时间：
2021-04-22
期刊：
影响因子：
2.4
通讯作者：
Mao S
中科院分区：
文献类型：
--
作者：
Zhu Y;Li W;Yang B;Qian R;Wu F;He X;Zhu Q;Liu J;Ni Y;Wang J;Mao S
背景调查COVID-19疫情期间防护措施和隔离对儿童呼吸道感染的影响。方法我们从浙江大学医学院附属儿童医院电子病历中提取了COVID-19疫情期间（2020年1月至4月）门诊就诊和呼吸道感染就诊数据以及呼吸道病毒（腺病毒（ADV）、甲型流感（FluA）、乙型流感（FluB）和呼吸道合胞病毒（RSV））检测数据，并进行比较结果我们发现，2020年1月门诊人次与2018年和2019年相当，但2月至4月期间分别下降了59.9%（288,003人次 vs. 717,983人次）和57.4%（288,003人次 vs. 676,704人次）。 2020年，与2018年和2019年同期相比。2020年1月至4月呼吸道感染总数比2018年和2019年同期分别下降65.7%（119,532例比348,762例）和59.0%（119,532例比291,557例）。与2018年和2019年同期相比，疫情期间感染人数也有所下降（P<0.001）。 我们还发现，2020 年 2 月至 4 月期间，已完成的呼吸道病毒检测以及 ADV、FluA、FluB 和 RSV 阳性病例数量显着减少。结论在这项研究中，我们发现在 COVID-19 爆发期间，门诊就诊量和儿童呼吸道感染显着减少。对儿童采取充分的防护措施和隔离可能有助于预防儿童呼吸道病毒感染。
BackgroundTo investigate the impact of protective measures and isolation on respiratory tract infections in children during the COVID-19 outbreak.MethodsWe extracted data on outpatient visits and respiratory infection visits, and tests of respiratory viruses (adenovirus (ADV), influenza A (FluA), influenza B (FluB) and respiratory syncytial virus (RSV)) from electronic healthcare records in Children’s Hospital, Zhejiang University School of Medicine during the COVID-19 outbreak (January–April, 2020), compared with those in 2018 and 2019 during the same periods.ResultsWe found that outpatient visits in January, 2020 was comparable with those in 2018 and 2019, but decreased by 59.9% (288,003 vs. 717,983) and 57.4% (288,003 vs. 676,704), respectively during the period of February-April, 2020, as compared with the same periods in 2018 and 2019. The total number of respiratory tract infections from January to April 2020 decreased by 65.7% (119,532 vs.348,762) and 59.0% (119,532 vs.291,557), respectively compared with the same periods in 2018 and 2019. The proportion of respiratory tract infections during the outbreak also dropped compared with the same periods in 2018 and 2019 (P<0.001). We also found significantly decreased number of completed tests for respiratory viruses and positive cases of ADV, FluA, FluB, and RSV during February-April, 2020.ConclusionsIn this study, we found that outpatient visits and respiratory tract infections in children significantly decreased during COVID-19 outbreak. Adequate protective measures and isolation in children may help to prevent respiratory virus infections in children.
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影响因子：
2.6
作者：
Yu, Pengbo;Ma, Chaofeng;Xu, Jiru
通讯作者：
Xu, Jiru
DOI：
10.12659/msm.908483
发表时间：
2018-03-30
期刊：
Medical science monitor : international medical journal of experimental and clinical research
影响因子：
--
作者：
Ge X;Guo Y;Chen J;Hu R;Feng X
通讯作者：
Feng X
影响因子：
3.3
作者：
Weber, MW;Mulholland, EK;Greenwood, BM
通讯作者：
Greenwood, BM
影响因子：
11.8
作者：
Hong, JY;Lee, HJ;Kim, WS
通讯作者：
Kim, WS
影响因子：
12.7
作者：
Wang, Dan;Chen, Liling;Zhao, Genming
通讯作者：
Zhao, Genming