Brood size moderates associations between relative size, telomere length, and immune development in European starling nestlings.
Brood size moderates associations between relative size, telomere length, and immune development in European starling nestlings.
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育雏尺寸调节了欧洲Starling Nestlings的相对大小，端粒长度和免疫发育之间的关联。
DOI：
10.1002/ece3.2551
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发表时间：
2016-11
影响因子：
2.6
通讯作者：
Bateson, Melissa
中科院分区：
文献类型：
--
作者：
Nettle, Daniel;Andrews, Clare;Reichert, Sophie;Bedford, Tom;Gott, Annie;Parker, Craig;Kolenda, Claire;Martin-Ruiz, Carmen;Monaghan, Pat;Bateson, Melissa
对于巢中的幼鸟来说，身体大小可能会影响发育的其他方面，如端粒长度和免疫功能。然而，可以预测任何方向的关联。一方面，生长和端粒维持之间可能存在权衡，生长和免疫功能投资之间可能存在权衡，这表明存在负相关性。另一方面，相对较大的个体可能会与他们的巢友竞争，使他们能够获得更多的资源，从而导致正相关。我们研究了34个巢的野生欧洲椋鸟，Sturnus vulgaris的雏鸟期的发展。在较大的窝中，窝内竞争通常更激烈。因此，我们预测，身体大小应该成为一个越来越积极的预测端粒长度和免疫功能的育雏大小增加。部分支持我们的预测，在预测红细胞端粒长度变化和细胞因子白细胞介素-6的血浆水平方面，育雏大小和体型之间存在显着的相互作用。体型大小和这些结果之间的关联从最小的育雏中的负面到最大的育雏中的正面。另一个免疫标记物，高敏C反应蛋白，显示没有系统的模式与身体大小或育雏大小。我们的研究结果证实，雏鸟生长的大小是重要的端粒动态和免疫系统的发展，但表型协会是由竞争环境缓和。
For young birds in a nest, body size may have implications for other aspects of development such as telomere length and immune function. However, it is possible to predict associations in either direction. On the one hand, there may be trade‐offs between growth and telomere maintenance, and growth and investment in immune function, suggesting there will be negative correlations. On the other hand, relatively larger individuals might be advantaged in competition with their nest‐mates, allowing them to garner more resources overall, leading to positive correlations. We studied development over the nestling period in 34 nests of wild European starlings, Sturnus vulgaris. Intrabrood competition is typically more intense in larger broods. Hence, we predicted that body size should become an increasingly positive predictor of telomere length and immune functioning as brood size increases. In partial support of our prediction, there were significant interactions between brood size and body size in predicting both erythrocyte telomere length change and plasma levels of the cytokine interleukin‐6. The associations between body size and these outcomes went from negative in the smallest broods to positive in the largest. A further immune marker, high‐sensitivity C‐reactive protein, showed no systematic patterning with body size or brood size. Our results confirm that the size to which a nestling grows is important for telomere dynamics and the development of the immune system, but the phenotypic associations are moderated by the competitive context.
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影响因子：
3.6
作者：
Goodenough, Anne E.;Stallwood, Bethan
通讯作者：
Stallwood, Bethan
影响因子：
2.8
作者：
Bernstein, Robin M.
通讯作者：
Bernstein, Robin M.
DOI：
10.1098/rspb.1999.0840
发表时间：
1999-09-07
影响因子：
4.7
作者：
Fair, JM;Hansen, ES;Ricklefs, RE
通讯作者：
Ricklefs, RE
影响因子：
3.5
作者：
Bartke A
通讯作者：
Bartke A
影响因子：
15.1
作者：
Demas, Gregory E.;Carlton, Elizabeth D.
通讯作者：
Carlton, Elizabeth D.