Prediction of the dependence of the line tension on the composition of linactants and the temperature in phase separated membranes.
Prediction of the dependence of the line tension on the composition of linactants and the temperature in phase separated membranes.
复制标题
预测线张力对相分离膜中的线性激活物的组成和温度的依赖性。
DOI：
10.1021/la502347a
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
S. Safran
中科院分区：
文献类型：
--
作者：
Benoit Palmieri;M. Grant;S. Safran
我们计算相分离，三元膜，包括线活性分子（linactants），往往会增加两个相分离物种的相容性域之间的线张力。预测的线张力，这取决于显着的linactant的组合物和温度，示出显着降低的膜中的linactants的分数增加朝向Lifshitz点，高于该点的膜相分离成调制相。我们预测了在接近混合转变的温度下零线张力的制度，并阐明了两种不同的方法，其中线张力可以降低：（1）线性作用物均匀分布在系统中，并减少两个体域之间的组成失配。(2)这些负作用物以择优取向在界面处聚集。这两种机制都在最近的实验和模拟中被观察到。第二个是独特的线活性分子，我们的工作表明，它是越来越重要的大部分的linactants和必要的出现制度的零线张力。该方法基于Palmieri和Safran提出的三元混合物模型[Palmieri，B.;萨夫兰，S。A. Langmuir 2013，29，5246]，并且线张力经由变分导出的自洽分布计算，用于界面区域中的组成和线性反应物取向的局部变化。
We calculate the line tension between domains in phase separated, ternary membranes that comprise line active molecules (linactants) that tend to increase the compatibility of the two phase separating species. The predicted line tension, which depends explicitly on the linactant composition and temperature, is shown to decrease significantly as the fraction of linactants in the membrane increases toward a Lifshitz point, above which the membrane phase separates into a modulated phase. We predict regimes of zero line tension at temperatures close to the mixing transition and clarify the two different ways in which the line tension can be reduced: (1) The linactants uniformly distribute in the system and reduce the compositional mismatch between the two bulk domains. (2) The linactants accumulate at the interface with a preferred orientation. Both of these mechanisms have been observed in recent experiments and simulations. The second one is unique to line active molecules, and our work shows that it is increasingly important at large fraction of linactants and is necessary for the emergence of a regime of zero line tension. The methodology is based on the ternary mixture model proposed by Palmieri and Safran [Palmieri, B.; Safran, S. A. Langmuir 2013, 29, 5246], and the line tension is calculated via variationally derived, self-consistent profiles for the local variation of composition and linactant orientation in the interface region.
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影响因子：
4
作者：
Veatch, Sarah L.;Cicuta, Pietro;Baird, Barbara
通讯作者：
Baird, Barbara
DOI：
10.1016/j.bbamem.2013.05.020
发表时间：
2013-09
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Konyakhina TM;Wu J;Mastroianni JD;Heberle FA;Feigenson GW
通讯作者：
Feigenson GW
DOI：
10.1103/physreve.89.022702
发表时间：
2014-02
期刊：
Physical review. E, Statistical, nonlinear, and soft matter physics
影响因子：
--
作者：
Amazon JJ;Feigenson GW
通讯作者：
Feigenson GW
影响因子：
3.4
作者：
Honerkamp-Smith, Aurelia R.;Veatch, Sarah L.;Keller, Sarah L.
通讯作者：
Keller, Sarah L.
DOI：
10.1073/pnas.1105996108
发表时间：
2011-07-12
影响因子：
11.1
作者：
Levental, Ilya;Grzybek, Michal;Simons, Kai
通讯作者：
Simons, Kai