Can a weight loss of one pound a week be achieved with a 3500-kcal deficit? Commentary on a commonly accepted rule.
Can a weight loss of one pound a week be achieved with a 3500-kcal deficit? Commentary on a commonly accepted rule.
复制标题
DOI：
10.1038/ijo.2013.51
复制
发表时间：
2013-12
影响因子：
4.9
通讯作者：
Heymsfield, S. B.
中科院分区：
文献类型：
--
作者：
Thomas, D. M.;Martin, C. K.;Lettieri, S.;Bredlau, C.;Kaiser, K.;Church, T.;Bouchard, C.;Heymsfield, S. B.
尽管理论证据表明，通常被称为3500千卡规则的模型严重高估了实际减肥效果，但3500千卡公式的广泛应用继续出现在教科书、受人尊敬的政府和健康相关网站以及科学研究出版物中。在这里，我们通过比较在完全监督或客观测量能量摄入的限制下进行的七个减肥实验的预测和实际体重减轻，来证明应用3500千卡规则的风险，即使作为一个方便的估计。我们提供了三个新开发的，可下载的应用程序，安装在Microsoft®Excel和Java中，模拟了严格验证的体重变化动态模型。在www.pbrc.edu/sswcp上提供的前两种工具提供了一种方便的替代方法，可以根据饮食摄入量的变化为患者提供预计体重减轻/增加的估计。第二个工具，可以从URL下载，www.pbrc.edu/mswcp，项目估计减肥同时为多个科目。该工具的开发是为了告知体重变化实验设计和分析。虽然复杂的动态模型可能无法直接处理，但新开发的工具提供了提供动态模型预测的机会，作为3500千卡规则的方便和更准确的替代方案。
Despite theoretical evidence that the model commonly referred to as the 3500 kcal rule grossly overestimates actual weight loss, widespread application of the 3500 kcal formula continues to appear in textbooks, on respected government and health related websites, and scientific research publications. Here we demonstrate the risk of applying the 3500 kcal rule even as a convenient estimate by comparing predicted against actual weight loss in seven weight loss experiments conducted in confinement under total supervision or objectively measured energy intake. We offer three newly developed, downloadable applications housed in Microsoft® Excel and Java which simulates a rigorously validated, dynamic model of weight change. The first two tools available at www.pbrc.edu/sswcp, provide a convenient alternative method for providing patients with projected weight loss/gain estimates in response to changes in dietary intake. The second tool which can be downloaded from the URL, www.pbrc.edu/mswcp, projects estimated weight loss simultaneously for multiple subjects. This tool was developed to inform weight change experimental design and analysis. While complex dynamic models may not be directly tractable, the newly developed tools offer the opportunity to deliver dynamic model predictions as a convenient and significantly more accurate alternative to the 3500 kcal rule.
登录
查看更多内容
影响因子：
7.1
作者：
Hall, Kevin D.;Chow, Carson C.
通讯作者：
Chow, Carson C.
影响因子：
168.9
作者：
Hall, Kevin D.;Sacks, Gary;Chandramohan, Dhruva;Chow, Carson C.;Wang, Y. Claire;Gortmaker, Steven L.;Swinburn, Boyd A.
通讯作者：
Swinburn, Boyd A.
影响因子：
1.5
作者：
Pope, Lizzy;Harvey-Berino, Jean;Ades, Phil
通讯作者：
Ades, Phil
影响因子：
7.1
作者：
WISHNOFSKY, M
通讯作者：
WISHNOFSKY, M
影响因子：
120.7
作者：
Heilbronn, LK;de Jonge, L;Ravussin, E
通讯作者：
Ravussin, E