Living electronics

Living electronics
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生活电子产品

DOI:
10.1007/s12274-019-2570-x
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发表时间:
2019
期刊:
影响因子:
9.9
通讯作者:
Jiang, Xiaocheng
Jiang, Xiaocheng
中科院分区:
材料科学1区
文献类型:
--
作者:
Zhang, Yixin;Hsu, Leo Huan-Hsuan;Jiang, Xiaocheng

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融合了生物和电子电路独特功能模式的生活电子产品有可能改变基本的生物物理/生物化学研究和转化生物医学/工程应用。本文综述了近年来克服生物/电子界面上固有的生理化学和信号错配的研究进展,重点介绍了通过以下途径实现功能协同的策略:(1)生物杂化电子学,将基因编码的生物机械与电子换能器杂交,以促进生物信号的翻译/解释;以及(2)生物合成电子学,其中生物电子通路被设计和编程以桥接内部生物电路和外部电路之间的差距。这些努力正在重建人工电子与生命系统通信的方式,并为生物合成,传感,能量转导和混合信息处理等许多跨学科应用开辟了新的可能性。
Living electronics that converges the unique functioning modality of biological and electrical circuits has the potential to transform both fundamental biophysical/biochemical inquiries and translational biomedical/engineering applications. This article will review recent progress in overcoming the intrinsic physiochemical and signaling mismatches at biological/electronic interfaces, with specific focus on strategic approaches in forging the functional synergy through: (1) biohybrid electronics, where genetically encoded bio-machineries are hybridized with electronic transducers to facilitate the translation/interpretation of biologically derived signals; and (2) biosynthetic electronics, where biogenic electron pathways are designed and programmed to bridge the gap between internal biological and external electrical circuits. These efforts are reconstructing the way that artificial electronics communicate with living systems, and opening up new possibilities for many cross-disciplinary applications in biosynthesis, sensing, energy transduction, and hybrid information processing.
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