Ecological niche modelling and predicted geographic distribution of Lutzomyia cruzi, vector of Leishmania infantum in South America.
Ecological niche modelling and predicted geographic distribution of Lutzomyia cruzi, vector of Leishmania infantum in South America.
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DOI：
10.1371/journal.pntd.0006684
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发表时间：
2018-07
影响因子：
3.8
通讯作者：
Carvalho BM
中科院分区：
文献类型：
--
作者：
Falcão de Oliveira E;Galati EAB;Oliveira AG;Rangel EF;Carvalho BM
在巴西婴儿利什曼原虫的一些传播疫源地中，克氏Lutzomyia可被认为是该病原体的主要媒介。此外，克氏乳杆菌是亚马孙乳杆菌的许可载体。它的地理分布似乎受到限制，仅限于塞拉多和潘塔纳尔生物群系，其中包括巴西和玻利维亚的一些地区。考虑到预测传播周期中涉及的物种分布是评估人类疾病风险的有效方法，本研究旨在利用基于气候和栖息地变量的多尺度生态位模型预测克氏L. crozi的空间分布。生态位模型用于确定南美洲环境适合这种特定病媒物种的地区，但没有记录其存在。根据文献、博物馆藏品和巴西卫生部门汇编了病媒发生记录。在五种生态位模型算法中，生物气候变量、海拔、土地利用和覆盖被用作预测因子：BIOCLIM、广义线性模型（逻辑回归）、最大熵、随机森林和支持向量机。病媒发生在年平均气温21.76 ~ 26.58℃，年总降水量1005 ~ 2048 mm的地区。城市地区主要出现在捕获地点附近。根据最终的生态位模型，克氏L. crozi的潜在分布区域横跨巴西和玻利维亚，在更大的气候有利区域内的适宜生境斑块中。这个合适区域的大部分位于巴西南马托格罗索州和马托格罗索州。我们的研究结果确定了在没有已知发生过沙蝇的地区环境适合克氏L. crozi的地区，因此建议进一步实地取样，特别是在南马托格罗索州Goiás州南部（与马托格罗索州、<s:1>圣保罗州和米纳斯吉拉斯州接壤）；在玻利维亚的圣克鲁斯省和埃尔贝尼省。利什曼病是由利什曼原虫寄生虫引起的媒介传播疾病，通过受感染的雌性沙蝇叮咬传播给人类。在巴西的一些特定地区，克氏卢佐米亚沙蝇是幼利什曼原虫的媒介，幼利什曼原虫是内脏利什曼病的病原体。利什曼原虫的传播对气候敏感，涉及寄生虫、媒介和宿主之间复杂的生态相互作用。考虑到病媒对气候和环境条件非常敏感，研究其地理分布对于了解VL的生态流行病学以及规划疾病控制行动具有重要意义。物种的生态位是决定其分布的关键因素。为此，本研究对南美克氏L. crozi的生态位进行了评价和建模，并对其易发地区进行了预测。根据最终的生态位模型，克氏L. crozi的潜在分布区域横跨巴西和玻利维亚，在气候有利地区的适宜生境斑块中。塞拉多和潘塔纳尔生物群落构成了这一适宜地区的最大部分，包括巴西的三个州和玻利维亚的一些地区。我们的研究结果加强了对沙蝇区系进行更多生态学研究的重要性。
In some transmission foci of Leishmania infantum in Brazil, Lutzomyia cruzi could be considered the main vector of this pathogen. In addition, L. cruzi is a permissive vector of L. amazonensis. Its geographical distribution seems to be restricted and limited to Cerrado and Pantanal biomes, which includes some areas in Brazil and Bolivia. Considering that predicting the distribution of the species involved in transmission cycles is an effective approach for assessing human disease risk, this study aims to predict the spatial distribution of L. cruzi using a multiscale ecological niche model based in both climate and habitat variables. Ecological niche modelling was used to identify areas in South America that are environmentally suitable for this particular vector species, but its presence is not recorded. Vector occurrence records were compiled from the literature, museum collections and Brazilian Health Departments. Bioclimatic variables, altitude, and land use and cover were used as predictors in five ecological niche model algorithms: BIOCLIM, generalised linear model (logistic regression), maximum entropy, random forests, and support vector machines. The vector occurs in areas where annual mean temperature values range from 21.76°C to 26.58°C, and annual total precipitation varies from 1005 mm and 2048 mm. Urban areas were most present around capture locations. The potential distribution area of L. cruzi according to the final ecological niche model spans Brazil and Bolivia in patches of suitable habitats inside a larger climatically favourable area. The bigger portion of this suitable area is located at Brazilian States of Mato Grosso do Sul and Mato Grosso. Our findings identified environmentally suitable areas for L. cruzi in regions without its known occurrence, so further field sampling of sand flies is recommended, especially in southern Goiás State, Mato Grosso do Sul (borders with Mato Grosso, São Paulo and Minas Gerais); and in Bolivian departments Santa Cruz and El Beni. Leishmaniases are vector-borne diseases caused by Leishmania parasites which are transmitted to humans by the bites of infected female sand flies. The sand fly Lutzomyia cruzi is the vector of Leishmania infantum, the causative agent of visceral leishmaniasis (VL), in some specific areas of Brazil. The transmission of Leishmania species is climate-sensitive and involves complex ecological interactions between parasites, vectors and hosts. Considering that the vectors are strongly sensitive to climatic and environmental conditions, studies of their geographical distribution are important for understanding the eco-epidemiology of VL, as well as for the planning of disease control actions. The ecological niche of a species is a critical determinant of its distribution. Therefore, we conducted a study to evaluate and model the ecological niche of L. cruzi and predict susceptible areas to its occurrence in South America. The potential distribution area of L. cruzi according to the final ecological niche model spans Brazil and Bolivia in patches of suitable habitats inside climatically favourable areas. Cerrado and Pantanal biomes comprise the biggest portion of this suitable area which includes three Brazilians states, and some areas in Bolivia. Our findings reinforce the importance of conducting more ecological studies on sand fly fauna.
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影响因子：
3.2
作者：
Casaril, Aline Etelvina;Nazario Monaco, Neiva Zandonaide;de Oliveira, Alessandra Gutierrez
通讯作者：
de Oliveira, Alessandra Gutierrez
影响因子：
2.8
作者：
Almeida PS;Sciamarelli A;Batista PM;Ferreira AD;Nascimento J;Raizer J;Andrade Filho JD;Gurgel-Gonçalves R
通讯作者：
Gurgel-Gonçalves R
影响因子：
1.2
作者：
Alvares, Clayton Alcarde;Stape, Jose Luiz;Sparovek, Gerd
通讯作者：
Sparovek, Gerd
影响因子：
3.8
作者：
de Oliveira, Everton Falcao;Oshiro, Elisa Teruya;Bianchi Galati, Eunice Aparecida
通讯作者：
Bianchi Galati, Eunice Aparecida
影响因子：
1.9
作者：
Dos Santos, SO;Arias, J;Malacco, MAF
通讯作者：
Malacco, MAF