Nucleic acids for the rational design of reaction circuits.
Nucleic acids for the rational design of reaction circuits.
复制标题
用于合理设计反应回路的核酸。
DOI:
10.1016/j.copbio.2012.11.011
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发表时间:
2013
影响因子:
7.7
通讯作者:
Y. Rondelez
中科院分区:
文献类型:
--
作者:
Adrien Padirac;T. Fujii;Y. Rondelez
Nucleic acid-based circuits are rationally designedin vitroassemblies that can perform complex preencoded programs. They can be used to mimicin silicocomputations. Recent works emphasized the modularity and robustness of these circuits, which allow their scaling-up. Another new development has led to dynamic, time-responsive systems that can display emergent behaviors like oscillations. These are closely related to biological architectures and provide anin vitromodel ofin vivoinformation processing. Nucleic acid circuits have already been used to handle various processes for technological or biotechnological purposes. Future applications of these chemical smart systems will benefit from the rapidly growing ability to design, construct, and model nucleic acid circuits of increasing size.
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影响因子:
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