Vapor-Deposited Biointerfaces and Bacteria: An Evolving Conversation.

Vapor-Deposited Biointerfaces and Bacteria: An Evolving Conversation.
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DOI:
10.1021/acsbiomaterials.9b01496
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发表时间:
2020-01-13
影响因子:
5.8
通讯作者:
Yang R
Yang R
中科院分区:
工程技术2区
文献类型:
--
作者:
Franklin T;Yang R

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在材料和微生物相遇的生物界面,有机和合成世界融合成一门新科学,指导用于生物应用的合成材料的设计和安全使用。气相沉积技术提供了一种有效的方法来控制这些生物界面的材料特性与分子水平的精度,这是重要的生物材料与细菌的界面。近年来,生物界面研究主要关注细菌与表面的相互作用,主要是为了杀灭细菌(抗菌)和防止污染(防污)。然而,气相沉积技术有可能创造出具有可以操纵和支配细菌行为而不是杀死或阻止它们的特征的生物界面。在这篇综述中,我们重点介绍了最近的进展,通过气相沉积产生的抗菌和抗菌生物界面,并提供了一个展望的机会,利用这些技术的特点,找到未开发的表面特征和微生物行为之间的连接。
At the biointerface where materials and microorganisms meet, the organic and synthetic worlds merge into a new science that directs the design and safe use of synthetic materials for biological applications. Vapor deposition techniques provide an effective way to control the material properties of these biointerfaces with molecular-level precision that is important for biomaterials to interface with bacteria. In recent years, biointerface research that focuses on bacteria−surface interactions has been primarily driven by the goals of killing bacteria (antimicrobial) and fouling prevention (antifouling). Nevertheless, vapor deposition techniques have the potential to create biointerfaces with features that can manipulate and dictate the behavior of bacteria rather than killing or deterring them. In this review, we focus on recent advances in antimicrobial and antifouling biointerfaces produced through vapor deposition and provide an outlook on opportunities to capitalize on the features of these techniques to find unexplored connections between surface features and microbial behavior.
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