Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers.
Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers.
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DOI：
10.3390/nu10030275
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发表时间：
2018-02-28
期刊：
影响因子：
5.9
通讯作者：
Blaak EE
中科院分区：
文献类型：
--
作者：
Müller M;Canfora EE;Blaak EE
胃肠道转运时间可能通过影响营养物质的吸收和微生物组成等机制，成为葡萄糖稳态和代谢健康的重要决定因素。调节胃肠道转运可能是膳食纤维有益健康效应的机制之一。这些影响包括改善葡萄糖稳态，降低患肥胖症和2型糖尿病等代谢性疾病的风险。在这篇综述中，我们首先讨论了胃排空率、小肠转运和结肠转运的调节，以及它们与葡萄糖稳态和代谢健康的关系。随后，我们简要介绍了不同膳食纤维对健康的影响，并讨论了纤维诱导的健康益处可能在多大程度上是通过调节胃肠道转运来实现的。
Gastrointestinal transit time may be an important determinant of glucose homeostasis and metabolic health through effects on nutrient absorption and microbial composition, among other mechanisms. Modulation of gastrointestinal transit may be one of the mechanisms underlying the beneficial health effects of dietary fibers. These effects include improved glucose homeostasis and a reduced risk of developing metabolic diseases such as obesity and type 2 diabetes mellitus. In this review, we first discuss the regulation of gastric emptying rate, small intestinal transit and colonic transit as well as their relation to glucose homeostasis and metabolic health. Subsequently, we briefly address the reported health effects of different dietary fibers and discuss to what extent the fiber-induced health benefits may be mediated through modulation of gastrointestinal transit.
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DOI：
10.1111/j.1467-789x.2012.01011.x
发表时间：
2012-10
期刊：
Obesity reviews : an official journal of the International Association for the Study of Obesity
影响因子：
--
作者：
Blaak EE;Antoine JM;Benton D;Björck I;Bozzetto L;Brouns F;Diamant M;Dye L;Hulshof T;Holst JJ;Lamport DJ;Laville M;Lawton CL;Meheust A;Nilson A;Normand S;Rivellese AA;Theis S;Torekov SS;Vinoy S
通讯作者：
Vinoy S
胃肠道营养输注部位和饮食行为：小肠内远端梯度近端的证据？
影响因子：
5.9
作者：
Alleleyn AM;van Avesaat M;Troost FJ;Masclee AA
通讯作者：
Masclee AA
影响因子：
3.7
作者：
Davis LM;Martínez I;Walter J;Goin C;Hutkins RW
通讯作者：
Hutkins RW
DOI：
10.1152/ajpgi.90286.2008
发表时间：
2008-08-01
影响因子：
4.5
作者：
Delgado-Aros, Silvia;Camilleri, Michael;Busciglio, Irene
通讯作者：
Busciglio, Irene
影响因子：
3.6
作者：
BLACKBURN, NA;HOLGATE, AM;READ, NW
通讯作者：
READ, NW