Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
复制标题
中药多糖靶向肠道菌群促进健康的分子机制
DOI:
10.1007/s11655-022-3522-y
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发表时间:
2022-05
影响因子:
2.9
通讯作者:
Shi-Jun Wang
中科院分区:
文献类型:
--
作者:
Wen-Xiao Zhao;Tong Wang;Ya-Nan Zhang;Qian Chen;Yuan Wang;Yan-Qing Xing;Jun Zheng;Chen-Chen Duan;Li-Jun Chen;Hai-Jun Zhao;Shi-Jun Wang
The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes mellitus, heart failure, and non-alcoholic fatty liver disease. Polysaccharides extracted from Chinese medicine (CM) can not only alleviate pathological status but also promote health by anti-inflammatory, regulating immunity, lowering blood glucose and lipids, anti-cancer, and anti-oxidation. The alterations of gut microbiota composition and metabolism pathways are the potential mechanisms of CM polysaccharides treatment. In addition, they exert functions through gut-organ axis or play an indirect role by synergistic actions with other drugs or components mediated by gut microbiota. This review summarizes the molecular mechanisms of CM polysaccharides interacted with intestinal microbial inhabitants as potential prebiotics for promoting health.
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DOI:
10.1016/j.ijbiomac.2019.09.007
发表时间:
2019
影响因子:
8.2
作者:
Wang Xu;Shi Linlin;Wang Xinping;Feng Yi;Wang Yuan
通讯作者:
Wang Yuan
影响因子:
6.1
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4.6
作者:
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Li SL
影响因子:
5.6
作者:
Wang Y;Fei Y;Liu L;Xiao Y;Pang Y;Kang J;Wang Z
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Wang Z
影响因子:
5.9
作者:
McNabney SM;Henagan TM
通讯作者:
Henagan TM