The Locus Coeruleus- Norepinephrine System in Stress and Arousal: Unraveling Historical, Current, and Future Perspectives.
The Locus Coeruleus- Norepinephrine System in Stress and Arousal: Unraveling Historical, Current, and Future Perspectives.
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DOI:
10.3389/fpsyt.2020.601519
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发表时间:
2020
影响因子:
4.7
通讯作者:
Van Bockstaele EJ
中科院分区:
文献类型:
--
作者:
Ross JA;Van Bockstaele EJ
Arousal may be understood on a spectrum, with excessive sleepiness, cognitive dysfunction, and inattention on one side, a wakeful state in the middle, and hypervigilance, panic, and psychosis on the other side. However, historically, the concepts of arousal and stress have been challenging to define as measurable experimental variables. Divergent efforts to study these subjects have given rise to several disciplines, including neurobiology, neuroendocrinology, and cognitive neuroscience. We discuss technological advancements that chronologically led to our current understanding of the arousal system, focusing on the multifaceted nucleus locus coeruleus. We share our contemporary perspective and the hypotheses of others in the context of our current technological capabilities and future developments that will be required to move forward in this area of research.
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DOI:
10.1017/s0140525x15001727
发表时间:
2016-01
期刊:
The Behavioral and brain sciences
影响因子:
--
作者:
Abdallah CG;Averill LA;Krystal JH;Southwick SM;Arnsten AF
通讯作者:
Arnsten AF
影响因子:
2.5
作者:
Aston-Jones, G;Cohen, JD
通讯作者:
Cohen, JD
影响因子:
3.3
作者:
AstonJones, G;Rajkowski, J;Kubiak, P
通讯作者:
Kubiak, P
影响因子:
--
作者:
Berger, H
通讯作者:
Berger, H
影响因子:
16.2
作者:
Arnsten AF;Wang MJ;Paspalas CD
通讯作者:
Paspalas CD