Enteroaggregative Escherichia coli.

Enteroaggregative Escherichia coli.
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DOI:
10.3201/eid0402.980212
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发表时间:
1998-04
影响因子:
11.8
通讯作者:
Guerrant RL
Guerrant RL
中科院分区:
医学2区
文献类型:
--
作者:
Nataro JP;Steiner T;Guerrant RL

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肠聚集性大肠杆菌 (EAEC) 是发展中国家儿童腹泻的一个日益被认识的原因,它与持续性腹泻(超过 14 天)尤其相关,而持续性腹泻是疾病和死亡的主要原因。最近爆​​发的疫情表明 EAEC 是工业化国家食源性疾病的一个原因。 EAEC感染的发病机制尚不清楚,但可以提出一种模型,其中EAEC粘附在肠粘膜上并产生肠毒素和细胞毒素,导致分泌性腹泻和粘膜损伤。 EAEC 刺激炎症介质释放的能力也可能在肠道疾病中发挥作用。
Enteroaggregative Escherichia coli (EAEC), an increasingly recognized cause of diarrhea in children in developing countries, has been particularly associated with persistent diarrhea (more than 14 days), a major cause of illness and death. Recent outbreaks implicate EAEC as a cause of foodborne illness in industrialized countries. The pathogenesis of EAEC infection is not well understood, but a model can be proposed in which EAEC adhere to the intestinal mucosa and elaborate enterotoxins and cytotoxins, which result in secretory diarrhea and mucosal damage. EAEC's ability to stimulate the release of inflammatory mediators may also play a role in intestinal illness.
DOI: 10.1016/0140-6736(91)90868-p
发表时间: 1991-02-02
期刊: LANCET
影响因子: 168.9
作者:
CRAVIOTO, A;TELLO, A;ESLAVA, C
通讯作者: ESLAVA, C
DOI: 10.1093/infdis/161.6.1249
发表时间: 1990-06-01
影响因子: 6.4
作者:
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通讯作者: LEVINE, MM
DOI: 10.1128/iai.65.10.4135-4145.1997
发表时间: 1997-10-01
影响因子: 3.1
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通讯作者: Nataro, JP
DOI: 10.1016/s0140-6736(96)12485-5
发表时间: 1997-06-07
期刊: LANCET
影响因子: 168.9
作者:
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通讯作者: Karch, H
DOI: 10.1093/oxfordjournals.aje.a009086
发表时间: 1997-01-15
影响因子: 5
作者:
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通讯作者: Sterling, CR