Shared Functions of Perirhinal and Parahippocampal Cortices: Implications for Cognitive Aging.
Shared Functions of Perirhinal and Parahippocampal Cortices: Implications for Cognitive Aging.
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DOI:
10.1016/j.tins.2018.03.001
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发表时间:
2018-06
影响因子:
15.9
通讯作者:
Ryan L
中科院分区:
文献类型:
--
作者:
Burke SN;Gaynor LS;Barnes CA;Bauer RM;Bizon JL;Roberson ED;Ryan L
A predominant view of perirhinal cortex (PRC) and postrhinal/parahippocampal cortex (POR/PHC) function contends that these structures are tuned to represent objects and spatial information, respectively. Known anatomical connectivity, along with recent electrophysiological, neuroimaging, and lesion data, however, indicate that both brain areas participate in spatial and nonspatial processing. Rather than content-based organization, the PRC and PHC/POR may participate in two computationally distinct cortical-hippocampal networks: one network tuned to process coarse information quickly, forming gist-like representations of scenes/environments; the other network tuned to process information about specific sensory details necessary for discrimination across sensory modalities. Available data suggest that the latter network may be more vulnerable in advanced age.
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