Integration of objects and space in perception and memory.

Integration of objects and space in perception and memory.
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DOI:
10.1038/nn.4657
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发表时间:
2017-10-26
影响因子:
25
通讯作者:
Knierim JJ
Knierim JJ
中科院分区:
医学1区
文献类型:
--
作者:
Connor CE;Knierim JJ

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对物体和空间的独特处理一直是研究高级视力和内侧颞叶记忆的组织原理。但是,在这里,我们讨论了对象和空间信息实际上如何紧密整合到视觉和记忆中。腹侧处理视觉途径带有精确的空间信息,从视网膜坐标转变为相对尺寸。在腹侧途径的最后阶段(包括面积TED),对象敏感的神经元与处理大规模环境空间的神经元混合。 TED主要针对周围皮层(PRC),该项目反过来又投射到侧向内嗅皮层(LEC)。中国和LEC还结合了对象和空间信息。例如,中国和LEC神经元展示了地标物体或对象的记忆位置所唤起的位置场。因此,在本地和全局尺度上的空间信息都深入整合到视觉和记忆中的腹侧/时间对象处理途径中。
Distinct processing of objects and space has been an organizing principle for studying higher-level vision and medial temporal lobe memory. Here, however, we discuss how object and spatial information are in fact closely integrated in vision and memory. The ventral, object-processing visual pathway carries precise spatial information, transformed from retinotopic coordinates into relative dimensions. At the final stages of the ventral pathway (including area TEd), object-sensitive neurons are intermixed with neurons that process large-scale environmental space. TEd projects primarily to perirhinal cortex (PRC), which in turn projects to lateral entorhinal cortex (LEC). PRC and LEC also combine object and spatial information. For example, PRC and LEC neurons exhibit place fields that are evoked by landmark objects or the remembered locations of objects. Thus, spatial information, on both local and global scales, is deeply integrated into the ventral/temporal object-processing pathway in vision and memory.
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