Pain killers: the interplay between nonsteroidal anti-inflammatory drugs and Clostridioides difficile infection.
Pain killers: the interplay between nonsteroidal anti-inflammatory drugs and Clostridioides difficile infection.
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DOI:
10.1016/j.mib.2021.11.011
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发表时间:
2022-03
影响因子:
5.4
通讯作者:
Zackular JP
中科院分区:
文献类型:
--
作者:
Soto Ocaña J;Bayard NU;Zackular JP
Clostridioides difficile is one of the leading causes of nosocomial infections worldwide. Increases in incidence, severity, and healthcare cost associated with C. difficile infection (CDI) have made this pathogen an urgent public health threat worldwide. The factors shaping the evolving epidemiology of CDI and impacting clinical outcomes of infection are not well understood, but involve tripartite interactions between the host, microbiota, and C. difficile. In addition to this, emerging data suggests an underappreciated role for environmental factors, such as diet and pharmaceutical drugs, in CDI. In this review, we discuss the role of nonsteroidal anti-inflammatory drugs (NSAIDs) and eicosanoids in CDI.
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DOI:
10.1126/science.aam9949
发表时间:
2017-08-11
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
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DOI:
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发表时间:
2013-10
期刊:
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影响因子:
--
作者:
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Tonolini M
DOI:
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发表时间:
2008-10-30
期刊:
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影响因子:
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通讯作者:
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影响因子:
7.3
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影响因子:
3.1
作者:
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