Articular Cartilage Assessment Using Ultrashort Echo Time MRI: A Review.

Articular Cartilage Assessment Using Ultrashort Echo Time MRI: A Review.
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DOI:
10.3389/fendo.2022.892961
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发表时间:
2022
影响因子:
5.2
通讯作者:
--
中科院分区:
医学2区
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--
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关节软骨是人类膝关节的主要组成部分,可能会受到与关节病理和/或衰老过程相关的各种退变机制的影响。超短回波时间(UTE)序列的TE小于100µS,能够检测到软骨中快弛豫和慢弛豫水质子的信号。这可以对所有的软骨层进行全面的评估,特别是对于包括深层和钙化区的短T2层。最近发展了几种超短回声时间(UTE)技术,用于形态成像和定量软骨评估。本文综述了目前基于UTE磁共振成像的膝关节成像技术,如T1、T1、ρ、磁化传递、双回波稳态、定量磁化率标测和反转恢复等。讨论了这些技术的对比机理及优缺点。
Articular cartilage is a major component of the human knee joint which may be affected by a variety of degenerative mechanisms associated with joint pathologies and/or the aging process. Ultrashort echo time (UTE) sequences with a TE less than 100 µs are capable of detecting signals from both fast- and slow-relaxing water protons in cartilage. This allows comprehensive evaluation of all the cartilage layers, especially for the short T2 layers which include the deep and calcified zones. Several ultrashort echo time (UTE) techniques have recently been developed for both morphological imaging and quantitative cartilage assessment. This review article summarizes the current catalog techniques based on UTE Magnetic Resonance Imaging (MRI) that have been utilized for such purposes in the human knee joint, such as T1, , T1ρ, magnetization transfer (MT), double echo steady state (DESS), quantitative susceptibility mapping (QSM) and inversion recovery (IR). The contrast mechanisms as well as the advantages and disadvantages of these techniques are discussed.
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