The Biomechanics of Cartilage-An Overview.

The Biomechanics of Cartilage-An Overview.
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DOI:
10.3390/life11040302
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发表时间:
2021-04-01
期刊:
Life (Basel, Switzerland)
影响因子:
--
通讯作者:
Migliorini F
Migliorini F
中科院分区:
其他
文献类型:
--
作者:
Eschweiler J;Horn N;Rath B;Betsch M;Baroncini A;Tingart M;Migliorini F

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关节软骨(AC)覆盖关节表面,并最大限度地减少关节炎中的摩擦。常驻细胞群软骨细胞被细胞外基质和大量蛋白质包围,这赋予了它们独特的特性。AC的特征在于具有不同机械性质的带状组成(浅表(切向)区、中间(过渡)区、深部区、钙化区)。概述了不同的测试(负载测试)方法以及不同的建模方法。广泛接受的生物力学测试方法,例如,压痕分析方法进行了总结和讨论。还示出了双相理论的描述。这是需要了解如何间隙水有助于对AC的粘弹性行为。此外,一个更复杂的模型的简短介绍。
Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given.
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