Cortical Activation during Action Observation, Action Execution, and Interpersonal Synchrony in Adults: A functional Near-Infrared Spectroscopy (fNIRS) Study.
Cortical Activation during Action Observation, Action Execution, and Interpersonal Synchrony in Adults: A functional Near-Infrared Spectroscopy (fNIRS) Study.
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DOI：
10.3389/fnhum.2017.00431
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发表时间：
2017
影响因子：
2.9
通讯作者：
Pelphrey KA
中科院分区：
文献类型：
--
作者：
Bhat AN;Hoffman MD;Trost SL;Culotta ML;Eilbott J;Tsuzuki D;Pelphrey KA
导读：人类参与人际同步（IPS），随着时间的推移，他们将自己的行为与社会伙伴的行为同步。当人类从事模仿/IPS行为时，额叶、颞叶和顶叶皮层的多个区域被激活，包括假定的镜像神经元系统（Iacoboni,； Buxbaum等人，）。在本研究中，我们比较了三种情况下基于fnir的皮层激活模式：动作观察（“观察”伙伴）、动作执行（自己“做”）和IPS（“一起”移动）。方法：15名正常发育的成年人用右臂完成伸手和清理任务，同时使用24通道日立近红外光谱系统检查皮质激活情况。每个成年人在三种情况下（观察、行动和一起）完成了8次试验。对于每个fNIRS通道，我们获得了氧合血红蛋白（HbO2）和脱氧血红蛋白（hbb）谱。空间配准方法用于定位每个通道下方的皮质区域，并定义六个感兴趣区域（roi），右侧和左侧上前（SA或中央前/后回），下后（IP或角/边缘上回）和下前（IA或颞上/中回）区域。结果：在任务相关差异方面，大多数roi在Do和Together时比Watch更活跃。只有右侧/同侧额顶叶和下顶叶皮层在“一起”时比“做”时有更大的激活。结论：在动作执行和IPS之间皮层激活的相似性表明，IPS的神经控制更类似于其执行而不是观察方面。需要明确的是，执行的操作越复杂，IPS行为就越困难。其次，IPS行为需要更多的右侧激活（与执行/观察相比），这表明IPS是一个高阶过程，与其子组件相比，涉及更多的双侧激活。这些发现为研究特殊人群（如有自闭症风险的婴儿和患有自闭症的儿童）的模仿和IPS障碍提供了一个神经影像学框架。
Introduction: Humans engage in Interpersonal Synchrony (IPS) as they synchronize their own actions with that of a social partner over time. When humans engage in imitation/IPS behaviors, multiple regions in the frontal, temporal, and parietal cortices are activated including the putative Mirror Neuron Systems (Iacoboni,; Buxbaum et al.,). In the present study, we compared fNIRS-based cortical activation patterns across three conditions of action observation (“Watch” partner), action execution (“Do” on your own), and IPS (move “Together”). Methods: Fifteen typically developing adults completed a reach and cleanup task with the right arm while cortical activation was examined using a 24-channel, Hitachi fNIRS system. Each adult completed 8 trials across three conditions (Watch, Do, and Together). For each fNIRS channel, we obtained oxy hemoglobin (HbO2) and deoxy hemoglobin (HHb) profiles. Spatial registration methods were applied to localize the cortical regions underneath each channel and to define six regions of interest (ROIs), right and left supero-anterior (SA or pre/post-central gyri), infero-posterior (IP or angular/supramarginal gyri), and infero-anterior (IA or superior/middle temporal gyri) regions. Results: In terms of task-related differences, the majority of the ROIs were more active during Do and Together compared to Watch. Only the right/ipsilateral fronto-parietal and inferior parietal cortices had greater activation during Together compared to Do. Conclusions: The similarities in cortical activation between action execution and IPS suggest that neural control of IPS is more similar to its execution than observational aspects. To be clear, the more complex the actions performed, the more difficult the IPS behaviors. Secondly, IPS behaviors required slightly more right-sided activation (vs. execution/observation) suggesting that IPS is a higher-order process involving more bilateral activation compared to its sub-components. These findings provide a neuroimaging framework to study imitation and IPS impairments in special populations such as infants at risk for and children with ASD.
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DOI：
10.1093/cercor/bhn181
发表时间：
2009-06
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Gazzola V;Keysers C
通讯作者：
Keysers C
影响因子：
3.4
作者：
Aslin RN
通讯作者：
Aslin RN
影响因子：
1.8
作者：
Grossman, ED;Blake, R
通讯作者：
Blake, R
影响因子：
2.5
作者：
Dewey, D
通讯作者：
Dewey, D
影响因子：
5.7
作者：
Caspers S;Zilles K;Laird AR;Eickhoff SB
通讯作者：
Eickhoff SB