Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies.
Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies.
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DOI：
10.1371/journal.pone.0027899
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
HALCyon study team
中科院分区：
文献类型：
--
作者：
Cooper R;Hardy R;Aihie Sayer A;Ben-Shlomo Y;Birnie K;Cooper C;Craig L;Deary IJ;Demakakos P;Gallacher J;McNeill G;Martin RM;Starr JM;Steptoe A;Kuh D;HALCyon study team
使用参与生命全程健康老龄化 (HALCyon) 研究计划的八个英国队列的数据，身体能力评估年龄范围为 50 至 90 岁以上，我们统一了身体能力客观测量数据（即握力、椅子上升能力、步行速度、定时起身和行走以及站立平衡表现），并调查了这些测量中的横截面年龄和性别差异。年龄较大的研究参与者的身体能力水平普遍较低，男性表现优于女性（例如，荟萃分析结果（N = 14,213（5项研究））发现，在调整年龄和体型后，男性的握力比女性高12.62公斤（11.34，13.90）），尽管在步行速度方面，这种性别差异在调整体型后有所减弱。还有证据表明，握力的性别差异随着年龄的增长而减小，而步行速度的性别差异则扩大（两种情况下年龄和性别之间的交互作用p<0.01）。这项研究不仅强调了身体能力客观测量中存在的年龄和性别差异，而且证明了几个大型队列研究数据的协调是可能的。这些统一的数据现在正在 HALCyon 中使用，以了解身体能力的终生社会和生物决定因素及其随年龄的变化。
Using data from eight UK cohorts participating in the Healthy Ageing across the Life Course (HALCyon) research programme, with ages at physical capability assessment ranging from 50 to 90+ years, we harmonised data on objective measures of physical capability (i.e. grip strength, chair rising ability, walking speed, timed get up and go, and standing balance performance) and investigated the cross-sectional age and gender differences in these measures. Levels of physical capability were generally lower in study participants of older ages, and men performed better than women (for example, results from meta-analyses (N = 14,213 (5 studies)), found that men had 12.62 kg (11.34, 13.90) higher grip strength than women after adjustment for age and body size), although for walking speed, this gender difference was attenuated after adjustment for body size. There was also evidence that the gender difference in grip strength diminished with increasing age,whereas the gender difference in walking speed widened (p<0.01 for interactions between age and gender in both cases). This study highlights not only the presence of age and gender differences in objective measures of physical capability but provides a demonstration that harmonisation of data from several large cohort studies is possible. These harmonised data are now being used within HALCyon to understand the lifetime social and biological determinants of physical capability and its changes with age.
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影响因子：
7
作者：
Curran, Patrick J.;Hussong, Andrea M.
通讯作者：
Hussong, Andrea M.
DOI：
10.1093/gerona/63.8.829
发表时间：
2008-08-01
影响因子：
5.1
作者：
Clark, Brian C.;Manini, Todd M.
通讯作者：
Manini, Todd M.
影响因子：
6.7
作者：
Bassey, EJ
通讯作者：
Bassey, EJ
影响因子：
7.8
作者：
Alfred T;Ben-Shlomo Y;Cooper R;Hardy R;Cooper C;Deary IJ;Elliott J;Gunnell D;Harris SE;Kivimaki M;Kumari M;Martin RM;Power C;Sayer AA;Starr JM;Kuh D;Day IN;HALCyon Study Team
通讯作者：
HALCyon Study Team
影响因子：
6.7
作者：
Bohannon, RW
通讯作者：
Bohannon, RW