Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use.
Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use.
复制标题
DOI：
10.1001/archgenpsychiatry.2008.509
复制
发表时间：
2009-01
影响因子：
--
通讯作者：
Preston, Kenzie L.
中科院分区：
文献类型：
--
作者：
Epstein, David H.;Willner-Reid, Jessica;Vahabzadeh, Massoud;Mezghanni, Mustapha;Lin, Jia-Ling;Preston, Kenzie L.
在生态瞬时评估（EMA）中，参与者以电子方式报告他们在真实的日常环境中的活动和情绪，从而实现对行为事件急性沉淀物的研究的真正前瞻性方法。EMA极大地增强了对烟草成瘾的研究，但很少尝试在可卡因或海洛因成瘾的个体中进行。前瞻性监测急性日常生活中的诱因，渴望和使用，可卡因和海洛因。队列研究。114名正在接受美沙酮治疗的可卡因和海洛因滥用门诊患者的志愿者样本在手持计算机上提供了14，918人日的EMA数据（每位参与者平均130.9天，范围6-189）。在这114例受试者中，共有102例（63例男性，39例女性）提供了急性预渴求或使用前数据，因此被纳入本分析。在每次自我报告的药物渴望或使用事件发生前5小时内，随机间隔报告情绪和暴露于12种假定药物使用触发因素的变化，通过重复测量logistic回归（SAS GLIMMIX宏）进行分析。在使用可卡因或海洛因渴望之前的5小时内，12个假定触发因素中的大多数呈线性增加。可卡因的使用与“锯药”（p<.0001）、“突然被诱惑使用”（p<.0001）、“想看看如果我使用会发生什么”（p<.0001）和“好心情”（p<.0001）的报告增加最密切相关。海洛因渴望与“悲伤”（p=.0002）和“愤怒”（p<.011）报告的增加相关性最强。对可卡因的渴望和海洛因的使用与任何评估的假定触发因素几乎没有可靠的联系。这些研究结果证实，滥用多种药物的个人可以在日常环境中使用手持计算机提供行为数据，这些数据可以揭示有序的模式，包括前瞻性地检测到的渴望和使用的预兆，这可能因药物而异。
In Ecological Momentary Assessment (EMA), participants electronically report their activities and moods in their daily environments in real time, enabling a truly prospective approach to the study of acute precipitants of behavioral events. EMA has greatly enhanced the study of tobacco addiction, but has rarely been attempted in individuals with cocaine or heroin addiction. To prospectively monitor the acute daily-life precipitants of craving for, and use of, cocaine and heroin. Cohort study. A volunteer sample of 114 cocaine- and heroin-abusing outpatients who were being treated with methadone provided EMA data on handheld computers for 14,918 person-days (mean 130.9 days per participant, range 6–189). Of those 114, a total of 102 (63 men, 39 women) provided acute pre-craving or pre-use data and were thus included in the present analyses. Changes in reports of mood and exposure to 12 putative drug-use triggers at random intervals during the five hours preceding each self-reported episode of drug craving or use, analyzed via repeated-measures logistic regression (SAS GLIMMIX macro). During the five hours preceding cocaine use or heroin craving, most of the 12 putative triggers showed linear increases. Cocaine use was most robustly associated with increases in reports of “Saw Drug” (p<.0001), “Tempted to use out of the blue” (p<.0001), “Wanted to see what would happen if I used” (p<.0001), and “Good mood” (p<.0001). Heroin craving was most robustly associated with increases in reports of “Sad” (p=.0002) and “Angry” (p<.011). Cocaine craving and heroin use showed few reliable associations with any of the putative triggers assessed. These findings confirm that polydrug-abusing individuals can provide behavioral data in their daily environments using handheld computers, and that those data can reveal orderly patterns, including prospectively detectable harbingers of craving and use, which may differ across drugs.
登录
查看更多内容
影响因子：
4.2
作者：
Hopper, James W.;Su, Zhaohui;Lukas, Scott E.
通讯作者：
Lukas, Scott E.
影响因子：
3.7
作者：
Gruber, K;Moran, PJ;Taylor, CB
通讯作者：
Taylor, CB
影响因子：
4.1
作者：
Barrett, LF;Barrett, DJ
通讯作者：
Barrett, DJ
影响因子：
3.9
作者：
McMahon, RC
通讯作者：
McMahon, RC
影响因子：
5.9
作者：
Shiffman, S;Waters, AJ
通讯作者：
Waters, AJ