Skeletal muscle fat infiltration: impact of age, inactivity, and exercise.

Skeletal muscle fat infiltration: impact of age, inactivity, and exercise.
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DOI:
10.1007/s12603-010-0081-2
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发表时间:
2010-05
影响因子:
5.8
通讯作者:
Lastayo, P. C.
Lastayo, P. C.
中科院分区:
医学3区
文献类型:
--
作者:
Marcus, R. L.;Addison, O.;Kidde, J. P.;Dibble, L. E.;Lastayo, P. C.

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大腿筋膜包膜或肌间脂肪组织(IMAT)内的脂肪浸润已被证明与老年人的不良代谢和活动障碍有关。最近的研究结果表明,这些脂肪沉积可能与年龄增加和不活动有关;也许运动可以抵消或减轻IMAT的增加。这份简短的报告总结了有关IMAT及其与老年人年龄增长、体力活动水平、肌肉力量、活动性和代谢的关系的文献。此外,我们提出的初步数据表明,IMAT与不同疾病状态下个体的年龄增加有关(r=0.47,p<0.05),并且抗阻运动可以降低患有各种共病的老年人的IMAT。
Fat infiltration within the fascial envelope of the thigh or intermuscular adispose tissue (IMAT), has been shown to be associated with both adverse metabolic and mobility impairments in older individuals. More recent findings suggest these fat deposits may be associated with increasing age and inactivity; and perhaps exercise may be able to counter or mitigate this increase in IMAT. This brief report summarizes the literature with respect to IMAT and its relationship to increasing age, physical activity levels, muscle strength, mobility and metabolism in the elderly. Further, we present preliminary data suggesting that IMAT is associated with increasing age in individuals across disease states (r=0.47, p<0.05), and that resistance exercise can decrease IMAT in older individuals with a variety of co-morbid conditions.
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发表时间: 2001-06-01
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