Utility of MRI in Quantifying Tissue Injury in Cervical Spondylotic Myelopathy.

Utility of MRI in Quantifying Tissue Injury in Cervical Spondylotic Myelopathy.
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DOI:
10.3390/jcm12093337
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发表时间:
2023-05-08
影响因子:
3.9
通讯作者:
Smith, Zachary A. A.
Smith, Zachary A. A.
中科院分区:
医学2区
文献类型:
--
作者:
Khan, Ali Fahim;Haynes, Grace;Mohammadi, Esmaeil;Muhammad, Fauziyya;Hameed, Sanaa;Smith, Zachary A. A.

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脊髓型颈椎病(CSM)是一种进行性疾病,如果不治疗,病情会随着时间的推移而恶化。然而,进展速度因人而异,并可能受到各种因素的影响,如患者的年龄、基础条件、脊髓压迫的严重程度和位置。早期诊断和及时治疗有助于减缓CSM的进展和改善症状。磁共振成像(MRI)方法在诊断和治疗CSM方面的应用越来越多。MRI方法提供颈脊髓和脑的详细图像和定量结构和功能数据,允许对组织损伤的程度和位置进行准确评估。本综述旨在提供MRI方法在CSM中枢神经系统功能和结构变化方面的应用理解。此外,我们确定了阻碍这些神经成像方法临床应用的几个挑战。
Cervical spondylotic myelopathy (CSM) is a progressive disease that worsens over time if untreated. However, the rate of progression can vary among individuals and may be influenced by various factors, such as the age of the patients, underlying conditions, and the severity and location of the spinal cord compression. Early diagnosis and prompt treatment can help slow the progression of CSM and improve symptoms. There has been an increased use of magnetic resonance imaging (MRI) methods in diagnosing and managing CSM. MRI methods provide detailed images and quantitative structural and functional data of the cervical spinal cord and brain, allowing for an accurate evaluation of the extent and location of tissue injury. This review aims to provide an understanding of the use of MRI methods in interrogating functional and structural changes in the central nervous system in CSM. Further, we identified several challenges hindering the clinical utility of these neuroimaging methods.
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