Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus.
Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus.
复制标题
DOI：
10.1002/art.24519
复制
发表时间：
2009-06-15
影响因子：
--
通讯作者：
Criswell, Lindsey A.
中科院分区：
文献类型：
--
作者：
Bachen, Elizabeth A.;Chesney, Margaret A.;Criswell, Lindsey A.
研究SLE患者心境和焦虑障碍的终生患病率。人口统计学和疾病相关变量与终身重度抑郁症和任何情绪或焦虑障碍的存在进行了检查。326例白人SLE女性患者完成了综合国际诊断访谈（CIDI）和系统性狼疮活动问卷（SLAQ），这是一项自我报告的SLE疾病活动性测量。采用二项式检验比较SLE患者与白人女性人群样本中精神病诊断的患病率。65%的参与者接受了终身情绪或焦虑诊断。与白人女性相比，SLE患者中重度抑郁症（47%）、特异性恐怖症（24%）、惊恐障碍（16%）、强迫症（9%）和双相I型障碍（6%）更常见（特异性恐怖症p = 0.00009，所有其他p值= 0.00001）。虽然大多数有心境障碍病史的患者向医疗机构报告了他们的精神症状，但相当数量的焦虑症患者没有。在控制了人口统计学和临床特征后，自我报告的疾病活动与终生抑郁症史（p = 0.001）和情绪或焦虑障碍（p = 0.001）相关。与一般人群相比，SLE女性患者中的几种情绪和焦虑障碍更常见，疾病活动可能导致这种较高的风险。简短的自我报告问卷可以帮助提供者识别患有这些疾病的患者，特别是当患者不愿意透露他们的症状时。
To examine the lifetime prevalence of mood and anxiety disorders in patients with SLE. Demographic and disease-related variables were examined for association with lifetime major depressive disorder and the presence of any mood or anxiety disorder. Three-hundred and twenty-six Caucasian women with SLE completed the Composite International Diagnostic Interview (CIDI) and the Systemic Lupus Activity Questionnaire (SLAQ), a self-report measure of disease activity in SLE. The binomial test was used to compare the prevalence of psychiatric diagnoses in SLE patients to a population sample of Caucasian women. Sixty-five percent of participants received a lifetime mood or anxiety diagnosis. Major depressive disorder (47%), specific phobia (24%), panic disorder (16%), obsessive-compulsive disorder (9%), and bipolar I disorder (6%) were more common among the SLE patients compared to Caucasian women (p = 0.00009 for specific phobia, all other p values = 0.00001). Although most patients with histories of mood disorders reported their psychiatric symptoms to a medical provider, a substantial number of patients with anxiety disorders did not. Self-reported disease activity was associated with a lifetime history of major depression (p = 0.001) and presence of a mood or anxiety disorder (p = 0.001), after controlling for demographic and clinical characteristics. Several mood and anxiety disorders are more common in women with SLE compared to the general population, and disease activity may contribute to this higher risk. Brief self-report questionnaires may help providers identify patients with these conditions, particularly when patients are reluctant to disclose their symptoms.
登录
查看更多内容
影响因子：
--
作者：
MCKINLEY, PS;OUELLETTE, SC;WINKEL, GH
通讯作者：
WINKEL, GH
影响因子：
--
作者：
MCCARTY, DJ;MANZI, S;KWOH, CK
通讯作者：
KWOH, CK
影响因子：
3.1
作者：
Means-Christensen, A;Sherbourne, CD;Stein, MB
通讯作者：
Stein, MB
影响因子：
1.6
作者：
MIGUEL, EC;PEREIRA, RMR;GENTIL, V
通讯作者：
GENTIL, V
影响因子：
--
作者：
Kessler, RC;Berglund, P;Walters, EE
通讯作者：
Walters, EE