MCP-Net: Inter-frame Motion Correction with Patlak Regularization for Whole-body Dynamic PET.
MCP-Net: Inter-frame Motion Correction with Patlak Regularization for Whole-body Dynamic PET.
复制标题
MCP-Net：针对全身动态 PET 的采用 Patlak 正则化的帧间运动校正。
DOI：
10.1007/978-3-031-16440-8_16
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Dvornek,NichaC
中科院分区：
文献类型：
--
作者：
Guo,Xueqi;Zhou,Bo;Chen,Xiongchao;Liu,Chi;Dvornek,NichaC
Inter-frame patient motion introduces spatial misalignment and degrades parametric imaging in whole-body dynamic positron emission tomography (PET). Most current deep learning inter-frame motion correction works consider only the image registration problem, ignoring tracer kinetics. We propose an inter-frame Motion Correction framework with Patlak regularization (MCP-Net) to directly optimize the Patlak fitting error and further improve model performance. The MCP-Net contains three modules: a motion estimation module consisting of a multiple-frame 3-D U-Net with a convolutional long short-term memory layer combined at the bottleneck; an image warping module that performs spatial transformation; and an analytical Patlak module that estimates Patlak fitting with the motion-corrected frames and the individual input function. A Patlak loss penalization term using mean squared percentage fitting error is introduced to the loss function in addition to image similarity measurement and displacement gradient loss. Following motion correction, the parametric images were generated by standard Patlak analysis. Compared with both traditional and deep learning benchmarks, our network further corrected the residual spatial mismatch in the dynamic frames, improved the spatial alignment of Patlak/images, and reduced normalized fitting error. With the utilization of tracer dynamics and enhanced network performance, MCP-Net has the potential for further improving the quantitative accuracy of dynamic PET. Our code is released at https://github.com/gxq1998/MCP-Net.
登录
查看更多内容
心房钠尿因子抑制肾上腺素能克隆细胞系 (PC12) 中去甲肾上腺素的释放。
影响因子：
5
作者：
Drewett,J;Marchand,G;Ziegler,R;Trachte,G
通讯作者：
Trachte,G
DOI：
--
发表时间：
1989
期刊：
The Journal of laboratory and clinical medicine
影响因子：
--
作者：
Morgan,DA;Peuler,JD;Koepke,JP;Mark,AL;DiBona,GF
通讯作者：
DiBona,GF
周围交感神经活动与心房钠尿因子之间的新兴关系。
影响因子：
6.1
作者：
O. Kuchel;W. Debinski;K. Rácz;N. Buu;R. Garcia;J. Cusson;P. Larochelle;M. Cantin;J. Genest
通讯作者：
J. Genest
心房钠尿因子抑制离体灌注大鼠肠系膜动脉中交感神经刺激引起的去甲肾上腺素释放。
影响因子：
5
作者：
Nakamaru,M;Inagami,T
通讯作者：
Inagami,T
加压素和心房钠尿肽之间的相互作用。
影响因子：
5.2
作者：
Thrasher,TN;Ramsay,DJ
通讯作者：
Ramsay,DJ