Research Review: What have we learned about adolescent substance use?
Research Review: What have we learned about adolescent substance use?
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研究回顾：关于青少年药物滥用，我们了解了什么？
DOI：
10.1111/jcpp.12783
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发表时间：
2018-06
期刊：
影响因子：
--
通讯作者：
Squeglia LM
中科院分区：
文献类型：
--
作者：
Gray KM;Squeglia LM
青春期是一个关键的生物，心理和社会发展阶段，涉及药物使用和相关不良后果的风险增加。这篇综述综合了关于这一复杂主题的新发现，旨在为关注青少年的研究和临床护理提供信息。使用PubMed进行了文献检索，得到了一个关注青少年物质使用的观察性和干预性研究的横截面。调查结果进行了组织和分类，以涵盖流行病学，神经生物学，预防和治疗的关键领域。青少年与物质有关的态度和使用模式随着时间的推移而演变，并受到成人和同龄人行为、公共政策、媒体信息、物质供应和其他变量的影响。许多风险和弹性因素导致了物质使用和相关后果的个体差异。观察技术的进步提高了对青少年大脑发育及其对物质使用的影响的理解。预防工作取得的结果喜忧参半，虽然已经开发了一些针对药物使用障碍的循证治疗方法，但效果一般不大，这表明需要进一步研究以加强预防和治疗成果。青少年的药物使用是异质性的，从规范到病理，并可能导致严重的急性和长期的发病率和死亡率。了解风险和弹性因素，潜在的神经生物学和最佳的发育敏感干预措施对于解决青春期物质相关问题至关重要。
Adolescence is a critical biological, psychological, and social developmental stage involving heightened risk for substance use and associated adverse consequences. This review, synthesizing emerging findings on this complex topic, is intended to inform research and clinical care focused on adolescents. Literature searches were conducted using PubMed, yielding a cross-section of observational and interventional studies focused on adolescent substance use. Findings were organized and categorized to cover key areas of epidemiology, neurobiology, prevention, and treatment. Adolescent substance-related attitudes and use patterns have evolved over time, informed by adult and peer behaviors, public policy, media messaging, substance availability, and other variables. A number of risk and resiliency factors contribute to individual differences in substance use and related consequences. Advances in observational techniques have provided enhanced understanding of adolescent brain development, and its implications for substance use. Prevention efforts have yielded mixed results, and while a number of adolescent-targeted evidence-based treatments for substance use disorders have been developed, effect sizes are generally modest, indicating the need for further research to enhance prevention and treatment outcomes. Substance use in adolescence is heterogeneous, ranging from normative to pathological, and can lead to significant acute and long-term morbidity and mortality. Understanding risk and resiliency factors, underlying neurobiology, and optimal developmentally-sensitive interventions is critical in addressing substance-associated problems in adolescence.
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影响因子：
16.2
作者：
Giedd, Jay N.;Rapoport, Judith L.
通讯作者：
Rapoport, Judith L.
影响因子：
6.7
作者：
Enoch, Mary-Anne
通讯作者：
Enoch, Mary-Anne
影响因子：
7.6
作者：
Dube, S. R.;Miller, J. W.;Anda, R. F.
通讯作者：
Anda, R. F.
DOI：
10.15288/jsa.1979.40.89
发表时间：
1979-01-01
期刊：
JOURNAL OF STUDIES ON ALCOHOL
影响因子：
--
作者：
COTTON, NS
通讯作者：
COTTON, NS
影响因子：
5.3
作者：
Baker, Simon T. E.;Lubman, Dan I.;Fornito, Alex
通讯作者：
Fornito, Alex