A review and novel theoretical model of how negative emotions influence inflammation: The critical role of emotion regulation.
A review and novel theoretical model of how negative emotions influence inflammation: The critical role of emotion regulation.
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DOI：
10.1016/j.bbih.2021.100397
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发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
Renna ME
中科院分区：
文献类型：
--
作者：
Renna ME
心理困扰是生活中不可避免的一部分。基于临床心理学、健康心理学和心理神经免疫学（PNI）理论的研究已经确定了焦虑和悲伤等负面情绪与炎症之间的关系。如果没有适当的调节，负面情绪会对身体造成生物磨损，从而增加发病率和死亡率的风险。这篇综述讨论了以前可用的研究之间的关系，负性情绪和情绪调节与炎症之间的身体健康的成年人和慢性疾病。然后，我提出了一个新的全面的生物行为模型的负面情绪。这个模型强调负面情绪的影响及其对炎症加剧的贡献。此外，我还讨论了情绪调节（包括持续性过程，如担心和沉思）如何调解这种关联。负性情绪和情绪调节之间的关系可能是双向的，这个模型的实证研究应该特别寻求解开这些关系。该模型通过了解情绪因素如何改变炎症并加速生物衰老和疾病风险，为推进PNI研究提供了机会。
Psychological distress is an inevitable part of life. Research drawing on theories from clinical psychology, health psychology, and psychoneuroimmunology (PNI) has identified relationships between negative emotions such as anxiety and sadness with inflammation. When not regulated properly, negative emotions can create biological wear and tear on the body that can increase risk for morbidity and mortality. This review discusses previously available research on relationships between negative emotions and emotion regulation with inflammation among both physically healthy adults and those with chronic illnesses. I then present a novel comprehensive biobehavioral model of negative emotionality. This model emphasizes the influence of negative emotions and their contribution to heightened inflammation. Further, I also discuss how emotion regulation (including perseverative processes such as worry and rumination) mediates this association. The relationships between negative emotionality and emotion regulation may be bidirectional, and empirical investigation of this model should specifically seek to disentangle these relationships. The proposed model offers the opportunity to advance PNI research through understanding how emotional factors alter inflammation and contribute to accelerated biological aging and disease risk.
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