Assessment of MR compatibility of a PET insert developed for simultaneous multiparametric PET/MR imaging on an animal system operating at 7 T.

Assessment of MR compatibility of a PET insert developed for simultaneous multiparametric PET/MR imaging on an animal system operating at 7 T.
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DOI:
10.1002/mrm.22591
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发表时间:
2011-01
影响因子:
3.3
通讯作者:
Pichler, Bernd J.
Pichler, Bernd J.
中科院分区:
医学3区
文献类型:
--
作者:
Wehrl, Hans F.;Judenhofer, Martin S.;Thielscher, Axel;Martirosian, Petros;Schick, Fritz;Pichler, Bernd J.

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PET和MR在一个系统中的组合目前正在出现,并开辟了生命系统功能检查的新领域。本文报告了PET插件对MR成像的相关影响。测量了主磁场和射频场均匀性的基本条件,以及应用包括回波平面技术在内的常用MR序列类型时的图像质量和信噪比。此外,通过比较使用和不使用PET插入物的结果,测量了PET插入物对RF噪声水平和RF干扰的影响。评估了使用和不使用PET插入物时EPI成像的时间稳定性。当存在PET插入物时,显示信噪比的小但显著的降低,而B 0和B1均匀性以及RF噪声水平没有受到不利影响。EPI成像研究中发现了较高的信号强度漂移;然而,这可以通过后处理进行补偿。总之,本研究表明,PET插入物实际上可设计用于MR系统并在MR系统中使用,而不会对MR图像质量产生实质性影响。
The combination of PET and MR in one system is currently emerging and opens up new domains in the functional examinations of living systems. This paper reports on relevant influences of a PET insert on MR imaging. The basic conditions of main magnetic field and RF field homogeneity were measured as well as image quality and signal-to-noise ratio when applying the usual MR sequence types including echo-planar techniques. Moreover, the influence of the PET insert on the RF noise level and on RF interferences was measured by comparing results achieved with and without the PET insert. The temporal stability of EPI imaging with and without the PET insert was assessed. Small but significant decreases in the signal-to-noise ratio were revealed when the PET insert was present, whereas B0 and B1 homogeneity as well as RF noise level were not adversely affected. A higher signal intensity drift was found for EPI imaging studies; however, this can be compensated by post processing. In summary, this study shows that PET inserts can be designed for and used within an MR system practically, without substantially affecting the MR image quality.
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