Organization of food protection behavior is differentially influenced by 192 IgG-saporin lesions of either the medial septum or the nucleus basalis magnocellularis.
Organization of food protection behavior is differentially influenced by 192 IgG-saporin lesions of either the medial septum or the nucleus basalis magnocellularis.
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DOI：
10.1016/j.brainres.2008.09.018
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发表时间：
2008-11-19
期刊：
影响因子：
2.9
通讯作者：
Wallace, Douglas G.
中科院分区：
文献类型：
--
作者：
Martin, Megan M.;Winter, Shawn S.;Cheatwood, Joseph L.;Carter, Lynniece A.;Jones, Jeana L.;Weathered, Scott L.;Wagner, Steven J.;Wallace, Douglas G.
关键词：
会聚线的证据支持的注意机制的基底核（NB）的作用，然而，关于内侧隔行为（MS）的作用的争论仍在继续。最近的研究支持了作用的隔海马系统在网上处理内部产生的线索。目前的研究旨在研究大鼠食物保护行为中可能存在的双重分离，这是一种依赖于外部和内部信息来源的自然行为。该研究检查了将192 IgG-皂草素实质内注射到MS或NB中对食物保护行为组织的影响。NB胆碱能损伤减少了成功的食物保护行为的数量，同时保留了食物保护行为的时间组织。相比之下，MS胆碱能损伤破坏了食物保护行为的时间组织，同时保留了成功保护食物的能力。这些观察结果与NB和MS胆碱能系统对处理外部和内部信息源的贡献的双重分离是一致的，并为隔海马系统参与处理内部产生的线索提供了进一步的证据。
Converging lines of evidence have supported a role for the nucleus basalis magnocellularis (NB) in attentional mechanisms; however, debate continues regarding the role of the medial septum in behavior (MS). Recent studies have supported a role for the septohippocampal system in the online processing of internally generated cues. The current study was designed to investigate a possible double dissociation in rat food protection behavior, a natural behavior that has been shown to depend on external and internal sources of information. The study examined the effects of intraparenchymal injections of 192 IgG-saporin into either the MS or NB on the organization of food protection behavior. NB cholinergic lesions reduced the number of successful food protection behaviors while sparing the temporal organization of food protection behavior. In contrast, MS cholinergic lesions disrupted the temporal organization of food protection behavior while sparing the ability to successfully protect food items. These observations are consistent with a double dissociation of NB and MS cholinergic systems' contributions to processing external and internal sources of information and provide further evidence for the septohippocampal system's involvement in processing internally generated cues.
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影响因子：
2.5
作者：
AMARAL, DG;KURZ, J
通讯作者：
KURZ, J
影响因子：
1.9
作者：
BAXTER, MG;BUCCI, DJ;GALLAGHER, M
通讯作者：
GALLAGHER, M
DOI：
10.1007/bf01965961
发表时间：
1980-01-01
期刊：
EXPERIENTIA
影响因子：
--
作者：
ETIENNE, AS
通讯作者：
ETIENNE, AS
影响因子：
3.5
作者：
Bizon, JL;Han, JS;Gallagher, M
通讯作者：
Gallagher, M
影响因子：
2.7
作者：
Frielingsdorf, H;Thal, LJ;Pizzo, DP
通讯作者：
Pizzo, DP