Ultrathin conformal devices for precise and continuous thermal characterization of human skin.
Ultrathin conformal devices for precise and continuous thermal characterization of human skin.
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DOI：
10.1038/nmat3755
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发表时间：
2013-10
期刊：
影响因子：
41.2
通讯作者：
Rogers, John A.
中科院分区：
文献类型：
--
作者：
Webb, R. Chad;Bonifas, Andrew P.;Behnaz, Alex;Zhang, Yihui;Yu, Ki Jun;Cheng, Huanyu;Shi, Mingxing;Bian, Zuguang;Liu, Zhuangjian;Kim, Yun-Soung;Yeo, Woon-Hong;Park, Jae Suk;Song, Jizhou;Li, Yuhang;Huang, Yonggang;Gorbach, Alexander M.;Rogers, John A.
精确的皮肤温度测量可以与其他测量一起，提供有关心血管健康、认知状态、恶性肿瘤和人体生理学许多其他重要方面的临床相关信息。在这里，我们介绍了一种超薄、柔顺的皮肤式传感器/致动器技术，它可以柔韧地贴合到表皮上，提供其他方法无法提供的连续、准确的热特性。例如，皮肤温度的非侵入性空间测绘与毫开尔文精度，以及组织热导率的同时定量评估。这种装置也可以通过揭示血流和灌注对这些特性的时间动态影响的方式来实现。实验和理论研究建立了操作的基本原理，并确定了设备设计的工程指导方针。评估与心理活动、身体刺激和血管收缩/扩张相关的皮肤温度的细微变化，以及通过测量热导率准确测定皮肤水合作用，是一些重要的操作例子。
Precision thermometry of the skin can, together with other measurements, provide clinically relevant information about cardiovascular health, cognitive state, malignancy and many other important aspects of human physiology. Here, we introduce an ultrathin, compliant skin-like sensor/actuator technology that can pliably laminate onto the epidermis to provide continuous, accurate thermal characterizations that are unavailable with other methods. Examples include non-invasive spatial mapping of skin temperature with millikelvin precision, and simultaneous quantitative assessment of tissue thermal conductivity. Such devices can also be implemented in ways that reveal the time-dynamic influence of blood flow and perfusion on these properties. Experimental and theoretical studies establish the underlying principles of operation, and define engineering guidelines for device design. Evaluation of subtle variations in skin temperature associated with mental activity, physical stimulation and vasoconstriction/dilation along with accurate determination of skin hydration through measurements of thermal conductivity represent some important operational examples.
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充血性心力衰竭和β1阻滞治疗后的低频血流振荡。
影响因子：
3.1
作者：
Bernjak, A.;Clarkson, P. B. M.;McClintock, P. V. E.;Stefanovska, A.
通讯作者：
Stefanovska, A.
影响因子：
3.1
作者：
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Kato, Gregory J.
影响因子：
2.7
作者：
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Slovácek, K
影响因子：
3.1
作者：
Kvandal, Per;Landsverk, Svein Aslak;Kirkeboen, Knut Arvid
通讯作者：
Kirkeboen, Knut Arvid
影响因子：
56.9
作者：
Kim, Dae-Hyeong;Lu, Nanshu;Rogers, John A.
通讯作者：
Rogers, John A.