An opportunistic theory of cellular and systems consolidation.
An opportunistic theory of cellular and systems consolidation.
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DOI：
10.1016/j.tins.2011.06.003
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发表时间：
2011-10
影响因子：
15.9
通讯作者：
Wixted, John T.
中科院分区：
文献类型：
--
作者：
Mednick, Sara C.;Cai, Denise J.;Shuman, Tristan;Anagnostaras, Stephan;Wixted, John T.
记忆通常被归类为海马体依赖或非独立记忆，睡眠被发现促进了这两种记忆，但方式不同。在这篇评论文章中，我们探索了从睡眠中受益的海马体依赖记忆的细胞和系统巩固的最佳神经状态。我们认为，这两种通常被分开处理的巩固可能在时间上重叠，并共同受益于一段减少干扰的时期(在此期间没有形成新的记忆)。导致干扰减少的条件包括慢波睡眠(SWS)、NMDA受体拮抗剂、苯二氮类药物、酒精和乙酰胆碱拮抗剂。我们假设，海马区依赖记忆的巩固可能不依赖于SWS本身。相反，每当海马体没有被编码新记忆的任务占据时，大脑就会机会主义地巩固以前编码的记忆。
Memories are often classified as hippocampus-dependent or –independent, and sleep has been found to facilitate both, but in different ways. In this Opinion article, we explore the optimal neural state for cellular and systems consolidation of hippocampus-dependent memories that benefit from sleep. We suggest that these two kinds of consolidation, which are ordinarily treated separately, may overlap in time and jointly benefit from a period of reduced interference (during which no new memories are formed). Conditions that result in reduced interference include slow wave sleep (SWS), NMDA receptor antagonists, benzodiazepines, alcohol, and acetylcholine antagonists. We hypothesize that the consolidation of hippocampal-dependent memories may not depend on SWS per se. Instead, the brain opportunistically consolidates previously encoded memories whenever the hippocampus is not otherwise occupied by the task of encoding new memories.
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影响因子：
2.4
作者：
Comte, J. C.;Ravassard, P.;Salin, P. A.
通讯作者：
Salin, P. A.
DOI：
10.1590/s0100-879x2000000900002
发表时间：
2000-09-01
影响因子：
2.3
作者：
Baddeley, A;Bueno, O;Da Cunha, C
通讯作者：
Da Cunha, C
影响因子：
2.9
作者：
BUZSAKI, G
通讯作者：
BUZSAKI, G
影响因子：
25
作者：
Behrens, CJ;van den Boom, LP;Heinemann, U
通讯作者：
Heinemann, U
影响因子：
3.4
作者：
CURRAN, HV;BARROW, S;BERNIK, M
通讯作者：
BERNIK, M