Genomic Features of Cladobotryum dendroides, Which Causes Cobweb Disease in Edible Mushrooms, and Identification of Genes Related to Pathogenicity and Mycoparasitism
Genomic Features of Cladobotryum dendroides, Which Causes Cobweb Disease in Edible Mushrooms, and Identification of Genes Related to Pathogenicity and Mycoparasitism
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食用菌蜘蛛网病的树状枝芽孢菌基因组特征及致病性和菌寄生相关基因的鉴定
DOI：
10.3390/pathogens9030232
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发表时间：
2020-03
期刊：
影响因子：
3.7
通讯作者：
Xiao Shijun
中科院分区：
文献类型：
--
作者：
Xu Rong;Liu Xiaochen;Peng Bing;Liu Peibin;Li Zhuang;Dai Yueting;Xiao Shijun
树枝状枝葡萄孢菌（Cladobotryum dendroides）是引起食用菌蛛网病的主要病原真菌之一。我们以前的研究主要集中在该真菌的遗传和形态特征，以及其致病性和合适的杀菌剂的鉴定。然而，目前对该菌的基因组特征、致病基因及致病分子机制的研究还很少。树枝状。在此，我们报道了一个高质量的从头C。并与近缘真菌进行了比较。组装的C. Dendroides基因组全长36.69 Mb，由8个重叠群组成，N50为4.76 Mb。该基因组的大小与C. protrusum和C.前尿道系统发育分析表明，在肉座菌科，枝孢菌是更接近Mycogone比木霉，这是符合表型证据。一个显着的预测扩展的基因家族与致病性，毒力和适应性强。我们的研究结果将有助于了解真菌-真菌相互作用，并探索有效的管理策略，以控制蛛网病。
Cladobotryum dendroides, which causes cobweb disease in edible mushrooms, is one of the major fungal pathogens. Our previous studies focused on the genetic and morphological characterization of this fungus, as well as its pathogenicity and the identification of appropriate fungicides. However, little is known about the genome characters, pathogenic genes, and molecular pathogenic mechanisms of C. dendroides. Herein, we reported a high-quality de novo genomic sequence of C. dendroides and compared it with closely-related fungi. The assembled C. dendroides genome was 36.69 Mb, consisting of eight contigs, with an N50 of 4.76 Mb. This genome was similar in size to that of C. protrusum, and shared highly conserved syntenic blocks and a few inversions with C. protrusum. Phylogenetic analysis revealed that, within the Hypocreaceae, Cladobotryum was closer to Mycogone than to Trichoderma, which is consistent with phenotypic evidence. A significant number of the predicted expanded gene families were strongly associated with pathogenicity, virulence, and adaptation. Our findings will be instrumental for the understanding of fungi–fungi interactions, and for exploring efficient management strategies to control cobweb disease.
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影响因子：
12.3
作者：
Kubicek CP;Herrera-Estrella A;Seidl-Seiboth V;Martinez DA;Druzhinina IS;Thon M;Zeilinger S;Casas-Flores S;Horwitz BA;Mukherjee PK;Mukherjee M;Kredics L;Alcaraz LD;Aerts A;Antal Z;Atanasova L;Cervantes-Badillo MG;Challacombe J;Chertkov O;McCluskey K;Coulpier F;Deshpande N;von Döhren H;Ebbole DJ;Esquivel-Naranjo EU;Fekete E;Flipphi M;Glaser F;Gómez-Rodríguez EY;Gruber S;Han C;Henrissat B;Hermosa R;Hernández-Oñate M;Karaffa L;Kosti I;Le Crom S;Lindquist E;Lucas S;Lübeck M;Lübeck PS;Margeot A;Metz B;Misra M;Nevalainen H;Omann M;Packer N;Perrone G;Uresti-Rivera EE;Salamov A;Schmoll M;Seiboth B;Shapiro H;Sukno S;Tamayo-Ramos JA;Tisch D;Wiest A;Wilkinson HH;Zhang M;Coutinho PM;Kenerley CM;Monte E;Baker SE;Grigoriev IV
通讯作者：
Grigoriev IV
影响因子：
14.9
作者：
Grigoriev IV;Nikitin R;Haridas S;Kuo A;Ohm R;Otillar R;Riley R;Salamov A;Zhao X;Korzeniewski F;Smirnova T;Nordberg H;Dubchak I;Shabalov I
通讯作者：
Shabalov I
影响因子：
12.3
作者：
Zheng P;Xia Y;Xiao G;Xiong C;Hu X;Zhang S;Zheng H;Huang Y;Zhou Y;Wang S;Zhao GP;Liu X;St Leger RJ;Wang C
通讯作者：
Wang C
编码植物细胞壁降解酶的基因从植物相关宿主大规模横向转移到真菌寄生真菌木霉属
影响因子：
4.5
作者：
Druzhinina IS;Chenthamara K;Zhang J;Atanasova L;Yang D;Miao Y;Rahimi MJ;Grujic M;Cai F;Pourmehdi S;Salim KA;Pretzer C;Kopchinskiy AG;Henrissat B;Kuo A;Hundley H;Wang M;Aerts A;Salamov A;Lipzen A;LaButti K;Barry K;Grigoriev IV;Shen Q;Kubicek CP
通讯作者：
Kubicek CP
影响因子：
4.4
作者：
Aragona M;Minio A;Ferrarini A;Valente MT;Bagnaresi P;Orrù L;Tononi P;Zamperin G;Infantino A;Valè G;Cattivelli L;Delledonne M
通讯作者：
Delledonne M