Height-specific serum cholesterol levels in pubertal children: data from population-based Japanese school screening.

Height-specific serum cholesterol levels in pubertal children: data from population-based Japanese school screening.
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DOI:
10.2188/jea.je20100108
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发表时间:
2011
影响因子:
4.7
通讯作者:
Iki M
Iki M
中科院分区:
医学3区
文献类型:
--
作者:
Fujita Y;Kouda K;Nakamura H;Nishio N;Takeuchi H;Iki M

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据报道,青春期儿童身高与血脂水平呈负相关。为了制定青春期儿童正常血脂水平按身高分层的标准,我们使用基于人群的学校筛查数据检查了身高特异性胆固醇水平。对2002年至2007年在岩田市公立学校就读的10 151名10岁和14岁儿童(占目标人群的98.9%)的血清总胆固醇(TC)和高密度脂蛋白胆固醇(HDL-C)水平进行了调查。身高最低和最高五分位数的TC的第95百分位分别为:10岁男孩221和219 mg/dL, 14岁男孩215和203 mg/dL, 10岁女孩220和204 mg/dL, 14岁女孩226和214 mg/dL。身高最低和最高的五分位数的HDL-C在10岁男孩中分别为45和43 mg/dL, 14岁男孩中分别为43和40 mg/dL, 10岁女孩中分别为46和42 mg/dL, 14岁女孩中分别为47和44 mg/dL。这项研究提供了10岁和14岁儿童的身高特异性血脂水平。在评估青春期儿童的胆固醇水平时应考虑身高。
Inverse associations between height and serum lipid levels in pubertal children have been reported. To develop criteria for normal serum lipid levels stratified by height in pubertal children, we examined height-specific cholesterol levels, using data from a population-based school screening. Serum levels of total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were investigated in 10 151 children (98.9% of the target population) aged 10 and 14 years who attended public schools in Iwata City from 2002 through 2007. The 95th percentiles of TC in the lowest and highest quintiles of height were 221 and 219 mg/dL, respectively, in 10-year-old boys, 215 and 203 mg/dL in 14-year-old boys, 220 and 204 mg/dL in 10-year-old girls, and 226 and 214 mg/dL in 14-year-old girls. The fifth percentiles of HDL-C in the lowest and highest quintiles of height were 45 and 43 mg/dL in 10-year-old boys, 43 and 40 mg/dL in 14-year-old boys, 46 and 42 mg/dL in 10-year-old girls, and 47 and 44 mg/dL in 14-year-old girls. This study provided height-specific levels of serum lipids in 10-year-old and 14-year-old children. Height should be considered when evaluating cholesterol levels in pubertal children.
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