Fundamental principles in bacterial physiology-history, recent progress, and the future with focus on cell size control: a review.
Fundamental principles in bacterial physiology-history, recent progress, and the future with focus on cell size control: a review.
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DOI：
10.1088/1361-6633/aaa628
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发表时间：
2018-05
期刊：
影响因子：
--
通讯作者：
Scott M
中科院分区：
文献类型：
--
作者：
Jun S;Si F;Pugatch R;Scott M
细菌生理学是生物学的一个分支，旨在了解细胞繁殖的总体原理。细菌生理学中的许多重要问题本质上是定量的，该领域的主要贡献者经常汇集来自多个学科的工具和思维方式。这篇文章为任何对细菌生理学的基本问题感兴趣的人提供了自20世纪初以来发展起来的主要思想和方法的全面概述。本文分为两部分。在第一部分（第1至3节）中，我们回顾了从20世纪40年代到70年代初细菌生理学的第一个“黄金时代”，并提供了该时期主要参考文献的完整列表。在第二部分（第4至7节）中，我们解释了第一个黄金时代的开创性工作如何影响了对一般定量原理的各种重新发现和现代细菌生理学的重大进一步发展。具体来说，第4节介绍了细胞大小动态平衡的“加法器”原理的历史和当前进展。第5节讨论了粗粒化对细胞蛋白质组成的影响，以及粗粒化蛋白质组“部门”如何在不同的生长条件下重新平衡。第6节侧重于生理不变量，并解释了它们如何成为理解生长和细胞周期之间协调的关键，而细胞周期是稳态生长中细胞大小控制的基础。第7节概述了所有内部过程的时间组织如何实现平衡增长。在最后的第8节中，我们通过讨论该领域未来的剩余挑战来结束。
Bacterial physiology is a branch of biology that aims to understand overarching principles of cellular reproduction. Many important issues in bacterial physiology are inherently quantitative, and major contributors to the field have often brought together tools and ways of thinking from multiple disciplines. This article presents a comprehensive overview of major ideas and approaches developed since the early 20th century for anyone who is interested in the fundamental problems in bacterial physiology. This article is divided into two parts. In the first part (Sections 1 to 3), we review the first ‘golden era’ of bacterial physiology from the 1940s to early 1970s and provide a complete list of major references from that period. In the second part (Sections 4 to 7), we explain how the pioneering work from the first golden era has influenced various rediscoveries of general quantitative principles and significant further development in modern bacterial physiology. Specifically, Section 4 presents the history and current progress of the ‘adder’ principle of cell size homeostasis. Section 5 discusses the implications of coarse-graining the cellular protein composition, and how the coarse-grained proteome ‘sectors’ re-balance under different growth conditions. Section 6 focuses on physiological invariants, and explains how they are the key to understanding the coordination between growth and the cell cycle underlying cell size control in steady-state growth. Section 7 overviews how the temporal organization of all the internal processes enables balanced growth. In the final Section 8, we conclude by discussing the remaining challenges for the future in the field.
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DOI：
10.1099/00221287-65-1-23
发表时间：
1971-01-01
期刊：
JOURNAL OF GENERAL MICROBIOLOGY
影响因子：
--
作者：
ANAGNOSTOPOULOS, GD
通讯作者：
ANAGNOSTOPOULOS, GD
影响因子：
3.2
作者：
ALLMAN, R;SCHJERVEN, T;BOYE, E
通讯作者：
BOYE, E
影响因子：
2.6
作者：
ALDEA, M;HERRERO, E;TRUEBA, FJ
通讯作者：
TRUEBA, FJ
大肠杆菌复制和分裂周期中的随机性和稳态。
影响因子：
4.6
作者：
Adiciptaningrum A;Osella M;Moolman MC;Cosentino Lagomarsino M;Tans SJ
通讯作者：
Tans SJ
影响因子：
8.6
作者：
Amir, Ariel
通讯作者：
Amir, Ariel