Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functions.

Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functions.
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DOI:
10.1053/j.gastro.2009.11.045
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发表时间:
2010-01
期刊:
影响因子:
29.4
通讯作者:
Camilleri M
Camilleri M
中科院分区:
医学1区
文献类型:
--
作者:
Papathanasopoulos A;Camilleri M

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膳食纤维(DF)这个术语反映了天然食物来源、加工谷物和商业补充剂的异质组。几种形式的 DF 已被用作治疗代谢综合征(包括肥胖)表现的补充或替代药物。毫不奇怪,DF 在代谢综合征和体重控制方面的生物学功效存在很大差异。据报道,多种因素和机制是 DF 对代谢综合征和肥胖影响的中介因素。在这一系列机制中,胃感觉运动影响的调节似乎对于 DF 的效果至关重要,但也相当可变。本文重点介绍不同形式的纤维和补充剂对肥胖和代谢综合征、血糖、血脂异常、心血管风险的作用、作用机制和益处,并探讨 DF 对胃感觉运动功能和饱腹感的影响,以介导 DF 的这些作用。
Dietary fiber (DF) is a term that reflects to a heterogenous group of natural food sources, processed grains and commercial supplements. Several forms of DF have been used as complementary or alternative agents in the management of manifestations of the metabolic syndrome, including obesity. Not surprisingly, there is a great variation in the biological efficacy of DF in metabolic syndrome and body weight control. Diverse factors and mechanisms have been reported as mediators of the effects of DF on the metabolic syndrome and obesity. Among this array of mechanisms, the modulation of gastric sensorimotor influences appears to be crucial for the effects of DF, but also quite variable. This article focuses on the role, mechanism of action and benefits of different forms of fiber and supplements on obesity and metabolic syndrome, glycemia, dyslipidemia, cardiovascular risk, and explores the effects of DF on gastric sensorimotor function and satiety in mediating these actions of DF.
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