Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19.

Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19.
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天然产品及中药抗COVID-19的近期临床试验。

DOI:
10.1007/s12088-020-00919-x
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发表时间:
2021-03
影响因子:
3
通讯作者:
Kai G
Kai G
中科院分区:
生物学4区
文献类型:
--
作者:
Nile SH;Kai G

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新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)导致潜在致命的冠状病毒病19(COVID-19),在地球仪造成重大的健康和经济负担。目前,许多临床研究正在进行中,但仍然没有任何特定的批准疗法或药物可用于有效治疗COVID-19。本综述旨在分析已在www.clinicaltrials.gov和http://www.chictr.org.cn注册的各种临床研究,这些研究注册了天然植物药物和传统中药(TCM),以发现有效的治疗和预防COVID-19。共确定了46种和64种天然药物和中医药干预措施,主要确定了COVID-19感染的预防策略和可能的治疗方法。我们发现,大多数正在进行的临床试验都是使用天然化合物,如肝素和维生素C作为治疗剂和免疫增强剂来对抗COVID-19。传统中药及草药可有效用作COVID-19的预防疗法,并在成功进行临床试验后,这些潜在疗法可被世界各国推广。 在线版本包含补充材料,请访问(10.1007/s12088-020-00919-x)。
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or drug established for effective treatment of COVID-19. This review aimed to analyses various clinical studies which have been registered in www.clinicaltrials.gov and http://www.chictr.org.cn were registered with natural plant-based medicines and Traditional Chinese medicine (TCM) for discovering effective treatment and prevention of COVID-19. Total 46 and 64 natural drug and TCM interventions were identified which mainly determined the preventive strategies and possible treatments for COVID-19 infection. We identified that most of the clinical trial undergoing on natural compound like heparin and vitamin C as therapeutic agents and immune boosters for against COVID-19. Traditional Chinese medicines and herbal medicines can be effectively used as a preventive therapy against COVID-19 and after successful clinical trials and these potential therapies can be promoted by countries around the world. The online version contains supplementary material available at (10.1007/s12088-020-00919-x).
DOI: 10.1007/s12088-020-00913-3
发表时间: 2021-03
影响因子: 3
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