HIV infection and intravenous drug use: critical issues in transmission dynamics, infection outcomes, and prevention.

HIV infection and intravenous drug use: critical issues in transmission dynamics, infection outcomes, and prevention.
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HIV 感染和静脉吸毒:传播动态、感染结果和预防的关键问题。

DOI:
10.1093/clinids/10.1.151
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发表时间:
1988
期刊:
Reviews of infectious diseases
影响因子:
--
通讯作者:
Stoneburner,RL
Stoneburner,RL
中科院分区:
--
文献类型:
--
作者:
DesJarlais,DC;Friedman,SR;Stoneburner,RL

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在美国和欧洲,静脉吸毒者是感染人类免疫缺陷病毒(HIV)的第二大人群,也是最有可能将HIV传播给异性伴侣的人群,他们将在未来的艾滋病流行中发挥越来越重要的作用。本文综述了五个新出现的关键问题,艾滋病毒感染的静脉吸毒者。在流行病学方面,注射毒品和匿名共用注射器具的比率似乎与静脉注射吸毒者中艾滋病毒的快速传播有关,而静脉注射吸毒者的异性传播似乎以相对缓慢但恒定的速率发生。存在支持性别相关辅因子和持续药物注射辅因子的数据,但这些潜在辅因子的机制尚未确定。除了明显的艾滋病外,艾滋病毒感染似乎还导致静脉吸毒者中各种致命感染的发病率增加。一些预防研究表明,静脉吸毒者的风险降低积极,但迫切需要新的方法来提高风险降低量。
As the second largest group of persons to have been infected with human immunodeficiency virus (HIV), and the most likely to transmit HIV to heterosexual partners in the United States and Europe, iv drug users will play an increasingly important role in the future of the AIDS epidemic. This paper reviews five emerging critical issues regarding HIV infection among iv drug users. In epidemiology, rates of drug injection and anonymous sharing of injection equipment appear related to rapid spread of HIV among iv drug users, while heterosexual transmission from iv drug users appears to have been occurring at a relatively slow but constant rate. Data exist that support a gender-related cofactor and a continuing drug injection cofactor, but mechanisms for these potential cofactors have not been determined. Besides frank AIDS, HIV infection also appears to lead to epidemic-level increases in a variety of fatal infections among iv drug users. Several studies of prevention show active risk reduction among iv drug users, but new methods are urgently needed to increase amount of risk reduction.
了解纽约市静脉注射吸毒者的艾滋病和高危行为。
DOI: --
发表时间: 1987
期刊: AIDS (London)
影响因子: --
作者:
P. Selwyn;C. Feiner;Cox Cp;C. Lipshutz;Cohen Rl
通讯作者: Cohen Rl
为有艾滋病风险的静脉吸毒者提供“免费”针头:纽约市的最新发展。
DOI: 10.1056/nejm198512053132311
发表时间: 1985
期刊: The New England journal of medicine
影响因子: --
作者:
DesJarlais,DC;Hopkins,W
通讯作者: Hopkins,W
1987 年左右针对静脉吸毒者的艾滋病预防工作概述
DOI: --
发表时间: 1989
期刊:
影响因子: --
作者:
S. Friedman;D. D. Des Jarlais;D. Goldsmith
通讯作者: D. Goldsmith
苏格兰西部吸毒者体内的 HTLV-III 抗体:爱丁堡关联
DOI: --
发表时间: 1986
期刊: The Lancet
影响因子: --
作者:
E. Follet;A. Mcintyre;B. O'Donnell;G. Clements;U. Desselberger
通讯作者: U. Desselberger
DOI: 10.1136/bmj.292.6519.527
发表时间: 1986-02-22
影响因子: 105.7
作者:
ROBERTSON, JR;BUCKNALL, ABV;BRETTLE, RP
通讯作者: BRETTLE, RP