The neuropsychology of amphetamine and opiate dependence: implications for treatment.

The neuropsychology of amphetamine and opiate dependence: implications for treatment.
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DOI:
10.1007/s11065-007-9033-y
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发表时间:
2007-09
影响因子:
5.8
通讯作者:
Sahakian, Barbara J.
Sahakian, Barbara J.
中科院分区:
心理学2区
文献类型:
--
作者:
Ersche, Karen D.;Sahakian, Barbara J.

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长期使用安非他明和/或阿片类药物与多种认知缺陷有关,包括注意力、抑制控制、计划、决策、学习和记忆等领域。尽管安非他明和阿片类药物使用者在认知功能的各个方面都表现出明显的损害,但根据滥用物质的不同,损害情况明显不同。有证据表明吸毒者的认知障碍对治疗参与度和疗效产生负面影响,我们回顾了物质特异性对执行和记忆功能的缺陷,并讨论了在治疗干预期间解决这些问题的可能性。
Chronic use of amphetamines and/or opiates has been associated with a wide range of cognitive deficits, involving domains of attention, inhibitory control, planning, decision-making, learning and memory. Although both amphetamine and opiate users show marked impairment in various aspects of cognitive function, the impairment profile is distinctly different according to the substance of abuse. In light of evidence showing that cognitive impairment in drug users has a negative impact on treatment engagement and efficacy, we review substance-specific deficits on executive and memory function, and discuss possibilities to address these during treatment intervention.
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