Emerging synergy between nanotechnology and implantable biosensors: a review.

Emerging synergy between nanotechnology and implantable biosensors: a review.
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DOI:
10.1016/j.bios.2009.12.001
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发表时间:
2010-03-15
影响因子:
12.6
通讯作者:
Papadimitrakopoulos F
Papadimitrakopoulos F
中科院分区:
工程技术1区
文献类型:
--
作者:
Vaddiraju S;Tomazos I;Burgess DJ;Jain FC;Papadimitrakopoulos F

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用于连续监测代谢物的可植入生物传感器的开发是持续的科学和技术兴趣的领域。另一方面,纳米技术,一门处理纳米尺度材料特性的学科,正在发展成为增强这些生物传感器性能的有力工具。本文综述了植入式生物传感器的现状,突出了纳米技术和传感器性能之间的协同作用。重点放在电化学检测方法,鉴于其广泛的使用和大量的基于纳米技术的改进,在各个方面的电化学生物传感器的性能。最后,关于纳米材料的毒性和生物相容性的问题,沿着与未来的应用前景,纳米技术在植入式生物传感器,进行了讨论。
The development of implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interest. On the other hand, nanotechnology, a discipline which deals with the properties of materials at the nanoscale, is developing as a potent tool to enhance the performance of these biosensors. This article reviews the current state of implantable biosensors, highlighting the synergy between nanotechnology and sensor performance. Emphasis is placed on the electrochemical method of detection in light of its widespread usage and substantial nanotechnology-based improvements in various aspects of electrochemical biosensor performance. Finally, issues regarding toxicity and biocompatibility of nanomaterials, along with future prospects for the application of nanotechnology in implantable biosensors, are discussed.
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