Inflammation-induced lymphangiogenesis and lymphatic dysfunction.

Inflammation-induced lymphangiogenesis and lymphatic dysfunction.
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DOI:
10.1007/s10456-014-9416-7
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发表时间:
2014-04
期刊:
影响因子:
9.8
通讯作者:
von der Weid, Pierre-Yves
von der Weid, Pierre-Yves
中科院分区:
医学1区
文献类型:
--
作者:
Liao, Shan;von der Weid, Pierre-Yves

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The lymphatic system is intimately linked to tissue fluid homeostasis and immune cell trafficking. These functions are paramount in the establishment and development of an inflammatory response. In the past decade, an increasing number of reports has revealed that marked changes, such as lymphangiogenesis and lymphatic contractile dysfunction occur in both vascular and nodal parts of the lymphatic system during inflammation, as well as other disease processes. This review provides a critical update on the role of the lymphatic system in disease process such as chronic inflammation and cancer and examines the changes in lymphatic functions the diseases cause and the influence these changes have on the progression of the diseases.
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