Neurocognition in college-aged daily marijuana users.
Neurocognition in college-aged daily marijuana users.
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DOI：
10.1080/13803395.2014.893996
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发表时间：
2014
影响因子：
2.2
通讯作者：
Luciana M
中科院分区：
文献类型：
--
作者：
Becker MP;Collins PF;Luciana M
大麻是美国最常用的非法物质。使用，特别是当它发生在早期时，与执行功能，学习和记忆中的认知障碍有关。这项研究全面测量了认知能力以及共病精神病理学和物质使用史，以确定与年轻成人大麻使用相关的神经认知特征。将17岁之前开始使用大麻的大学年龄大麻使用者（n=35）与人口统计学匹配的对照组（n=35）进行比较。Maritime用户的功能很高，表现出与对照组相当的智商和相对更好的处理速度。Maritime用户表现出相对的认知障碍，在口头记忆，空间工作记忆，空间规划，和动机决策。同时使用酒精，这是更重的大麻使用者，意外地发现与更好的表现在这些领域的一些。这项研究提供了青少年和年轻人使用大麻的背景下神经认知障碍的额外证据。研究结果进行了讨论大麻的内在动机和离散方面的认知的影响。
Marijuana is the most commonly used illicit substance in the United States. Use, particularly when it occurs early, has been associated with cognitive impairments in executive functioning, learning, and memory. This study comprehensively measured cognitive ability as well as comorbid psychopathology and substance use history to determine the neurocognitive profile associated with young adult marijuana use. College-aged marijuana users who initiated use prior to age 17 (n=35) were compared to demographically-matched controls (n=35). Marijuana users were high functioning, demonstrating comparable IQs to controls and relatively better processing speed. Marijuana users demonstrated relative cognitive impairments in verbal memory, spatial working memory, spatial planning, and motivated decision-making. Comorbid use of alcohol, which was heavier in marijuana users, was unexpectedly found to be associated with better performance in some of these areas. This study provides additional evidence of neurocognitive impairment in the context of adolescent and young adult marijuana use. Findings are discussed in relation to marijuana’s effects on intrinsic motivation and discrete aspects of cognition.
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