The discovery of the first human retrovirus: HTLV-1 and HTLV-2.

The discovery of the first human retrovirus: HTLV-1 and HTLV-2.
复制标题

DOI:
10.1186/1742-4690-2-17
复制
发表时间:
2005-03-02
期刊:
影响因子:
3.3
通讯作者:
Gallo RC
Gallo RC
中科院分区:
医学2区
文献类型:
--
作者:
Gallo RC

文献摘要

参考文献

被引文献

相似文献

在此,我描述了直至并包括我的实验室发现第一种人类逆转录病毒HTLV - I及其近亲HTLV - II的历史。我的研究工作受到早期研究的启发,这些研究表明包括非人灵长类在内的多种动物的白血病存在逆转录病毒病因。我的两个主要研究方法是制定检测病毒逆转录酶的标准和方法,以及确定能够支持造血细胞生长的生长因子。在发现白细胞介素 - 2并将其用于培养成人T细胞淋巴瘤/白血病细胞之后,这些努力最终取得了成功。
I describe here the history leading up to and including my laboratory's discovery of the first human retrovirus, HTLV-I, and its close relative, HTLV-II. My efforts were inspired by early work showing a retroviral etiology for leukemias in various animals, including non-human primates. My two main approaches were to develop criteria for and methods for detection of viral reverse transcriptase and to identify growth factors that could support the growth of hematopoietic cells. These efforts finally yielded success following the discovery of IL-2 and its use to culture adult T cell lymphoma/leukemia cells.
DOI: 10.1126/science.181845
发表时间: 1976-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
MORGAN, DA;RUSCETTI, FW;GALLO, R
通讯作者: GALLO, R
DOI: 10.1038/newbio235170a0
发表时间: 1972-01-01
期刊: NATURE-NEW BIOLOGY
影响因子: --
作者:
KAWAKAMI, TG;DUNGWORTH, DL;GILDEN, RV
通讯作者: GILDEN, RV
DOI: 10.1073/pnas.77.12.7415
发表时间: 1980-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
POIESZ, BJ;RUSCETTI, FW;GALLO, RC
通讯作者: GALLO, RC
DOI: 10.1073/pnas.78.3.1887
发表时间: 1981-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
REITZ, MS;POIESZ, BJ;GALLO, RC
通讯作者: GALLO, RC
DOI: 10.1016/0006-291x(74)90635-4
发表时间: 1974-01-01
影响因子: 3.1
作者:
REITZ, MS;SMITH, RG;GALLO, RC
通讯作者: GALLO, RC