Sleep and alertness disturbance and substance use disorders: A bi-directional relation.

Sleep and alertness disturbance and substance use disorders: A bi-directional relation.
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DOI:
10.1016/j.pbb.2021.173153
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发表时间:
2021-04
期刊:
Pharmacology, biochemistry, and behavior
影响因子:
--
通讯作者:
Roth T
Roth T
中科院分区:
其他
文献类型:
--
作者:
Roehrs T;Sibai M;Roth T

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大多数描述睡眠/警觉性障碍与物质使用障碍(SUD)关系的文献都集中在滥用倾向物质对睡眠和警觉性的破坏性影响上。很少有研究或文献综述评估或讨论睡眠/警觉性障碍如何影响物质使用。本文重点关注这种关系的睡眠/警觉性障碍方面。我们认为,这种关系是双向的,并审查证据表明,睡眠/警觉性障碍影响成瘾周期的各个阶段,包括启动,维护和复发的SUD。我们回顾了成瘾周期各个阶段的各种物质,并得出结论,睡眠/警觉性障碍是理解和治疗SUD的关键因素。
The majority of the literature describing the relation of sleep/alertness disturbance and substance use disorders (SUD) has focused on the disruptive effects of substances with abuse liability on sleep and alertness. Rarely have studies or literature reviews assessed or discussed how sleep/alertness disturbance affects substance use. This paper focuses on the sleep/alertness disturbance side of the relation. We argue that the relation is bi-directional and review evidence showing that sleep/alertness disturbance affects all phases of the addiction cycle, including the initiation, maintenance and relapse of SUD. We review a variety of substances across all phases of the addiction cycle and conclude sleep/alertness disturbance is a critical factor in both understanding and treating SUD.
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