Sleep architecture in adolescent marijuana and alcohol users during acute and extended abstinence.

Sleep architecture in adolescent marijuana and alcohol users during acute and extended abstinence.
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DOI:
10.1016/j.addbeh.2009.05.011
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发表时间:
2009-11
影响因子:
4.4
通讯作者:
Tapert, Susan F.
Tapert, Susan F.
中科院分区:
医学2区
文献类型:
--
作者:
Cohen-Zion, Mairav;Drummond, Sean P. A.;Padula, Claudia B.;Winward, Jennifer;Kanady, Jennifer;Medina, Krista L.;Tapert, Susan F.

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这项研究调查了在青春期晚期停止使用大麻和酒精后的睡眠变化。29名重度大麻和酒精使用者和20名对照者在28天的监测戒断期间进行了研究。在第1-2夜和第27-28夜,研究了睡眠作为先前物质使用的函数。在第二个晚上,过去一个月的酒精摄入预测了快速眼动睡眠的百分比,而大麻摄入预测了慢波睡眠的百分比。到第28晚,酒精和大麻的使用都不能预测任何睡眠结构测量。然而,在第28夜,大麻和酒精的摄入可以预测睡眠中的周期性肢体运动(PLMs)指数。结果表明,在青少年中:(1)停止大量使用大麻和酒精可能会影响睡眠;(2)大多数睡眠异常在戒酒几周后减轻;(3)禁欲后PLMs可能增加。
This study examined sleep changes following cessation of marijuana and alcohol use during late adolescence. Twenty-nine heavy marijuana and alcohol users and 20 matched controls were studied during a 28-day monitored abstinence period. Sleep as examined as a function of prior substance use during Nights 1–2 and Nights 27–28. On Night 2, percent Rapid Eye Movement sleep was predicted by past month alcohol use, whereas percent Slow Wave Sleep was predicted by marijuana intake. By Night 28, neither alcohol no marijuana use predicted any sleep architecture measure. However, on Night 28, indices of period limb movements (PLMs) in sleep were predicted by marijuana and alcohol intake. Results indicate that in adolescents: (1) cessation of heavy marijuana and alcohol use may influence sleep; (2) most sleep abnormalities abate within several weeks of abstinence; and (3) PLMs may increase following abstinence.
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